BioAtla Investor Presentation Deck slide image

BioAtla Investor Presentation Deck

Encouraging Phase 1 results with CAB-ROR2 (BA3021) in refractory patients with NSCLC Maximum % Change from Baseline in Sum of Target Lesions bicatla 30% 20% 10% 0% -10% -20% -30% -40% -50% -60% ROR2 + (**TmPS=100) 1.2mg/kg d1,8 I I I I I Suboptimal dose (1.2mg/kg 2Q3W) ROR2 - (**TmPS=0) 3mg/kg d1 Patient experienced tumor shrinkage prior to progression of metastatic bone lesions Response at Variable Dosing ROR2 + (**TmPS=45) 3.3mg/kg d1 NSCLC squamous tumor: 10mm to 0mm on first scan Note: Not Evaluable (Strong, extensive fibroblastic stromal positivity reported) Not Evaluable 1.5mg/kg d1,8 ROR2 + (**TmPS=95) 3.3mg/kg d1 I ROR2 + (**TmPS=70) 3mg/kg d1 ¶ PR **Suboptimal dose 1.2 mg/kg 2Q3W. Tumor shrinkage occurred prior to progression of metastatic bone lesions. NSCLC squamous tumor 10mm to 0mm on first scan. ■ Two out of three ROR2+ patients had a partial response following BA3021 treatment BioAtla| Overview 44
View entire presentation