Ocuphire Pharma Investor Updates

P 22 Tolerability: Conjunctival Hyperemia (Redness) Score Minor Change (0.5 Point) In Redness Score Over The First 2 Hours In LDP Arms 4 Mean Hyperemia Score (4-point scale) 2 3 0 0 Mean Hyperemia Score (4-point Scale) Over Time 0.5 Placebo Alone (N=45) 1 2 Time (Hours) Nyxol + LDP (N=44) 3 4 -Nyxol Alone (N=30) Source: VEGA-1 TLR Table 14.3.3.2 Continuous Summary of Conjunctival Hyperemia by Time Point (Safety Population) 6 LDP (N=31) Severe (+3) Moderate (+2) Mild (+1) None (0) Scale for Conjunctival Hyperemia CCLRU Reference Ocuphire PHARMA

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