BioNTech Investor Presentation Deck

2022 Strategic Priorities. 27 Continue COVID-19 Vaccine Leadership Care • Label & geographic expansion. Variant-adapted and next- generation vaccines • Innovations for pandemic ● preparedness Execute in Oncology FIH, first-in-human;; Al, artificial intelligence Prepare for registrational trials Additional data for CAR-T cell therapy against solid tumors ● Expand in Infectious Disease Initiate 4 FIH vaccine trials: 10+ additional mRNA vaccine programs Precision antibacterials ● Advance into New Therapeutic Areas Autoimmune disease Regenerative medicine Cardiovascular disease Invest in Foundation to Enable Accelerated Innovation and Expansion Digital & Al Capabilities | Technologies | Development Team | Manufacturing | Global Footprint BIONTECH

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