23andMe Investor Presentation Deck
POWER: Combining Extensive Pleiotropy in the 23andMe Database and
Computational Biology for Target Discovery
Genetic insights
GWAS signals / pleiotropy (one
variant affecting multiple traits)
disease 1
disease 2
disease 3
disease 4
signal 1
signal 2
signal 3
signal 4
signal 5
signal 6
Computational Biology
ML / AI
QTL-based and custom ML
models for gene mapping and
target hypothesis prioritization
Interpretation of GWAS signals
making extensive use of
pleiotropy and allelic series and
to increase reliability of biological
conclusions
Analysis of bulk/single
cell/differential gene expression
Biological insights
genes, mechanisms, pathways
and cell types
Copyright © 2024 23and Me, Inc.
JAK/STAT
Th1/Th2 dif
Recept int
Th17 diff
23andMe
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