Orthofix Investor Presentation Deck

Complementary Portfolios Bridging Across Growing Markets ORTHOFIX® SeaSpine. Motion Preservation Spine Fixation Spinal Implants Trr Biologics Bone Growth Therapies Biologics & Regenerative Technologies Enabling Technologies Surgical Navigation System Preoperative Planning Software Orthopedics les $20B Total Addressable Market | 4.2% CAGR $7B of Focused Growth Segments* | 6.1 % CAGR SmartTRAK® 2022 2026 U.S. Estimates *Focused growth segments include Enabling Technologies, Motion Preservation, Interbody, DBM, LLIF/OLIF, MIS and Long Bone Stimulation Limb Reconstruction Deformity Correction

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