First-Quarter 2022 Earnings

First-Quarter 2022 Performance¹ Metric Sales Growth Reported Sales Growth Constant Currency Sales Growth Operational Adjusted Diluted EPS Growth vs. Prior-Year Period Baxter Q1 2022 Guidance 24% - 25% 27% -28% LSD2 Growth $0.79 - $0.82 4% -8% Q1 2022 Actual +26% +29% +3% $0.93 +22% Strong Adjusted EPS Performance Exceeds Guidance; Results Reflect Favorable Product Mix And Disciplined Execution On Acquisition Related Cost Synergies ¹Non-GAAP financial metrics referenced in this slide include constant currency sales growth, operational sales growth, and adjusted diluted EPS. A reconciliation to comparable U.S. GAAP measures can be found herein and is available at www.baxter.com. 2Low single digit. 8

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