Acute Therapies

Market Dynamics ~6% AKI Patient Growth Stable market growth driven by aging population and environmental factors¹ Baxter 1 JA Patient Co-Morbidities Increasing number of patients entering the ICU with co-morbidities3 iiii po ~200K Untreated Patients Large population of undiagnosed CRRT patients² ~50% Mortality Rate Half of patients entering the ICU with AKI requiring RRT do not recover4 Significant Opportunity To Increase Therapy Adoption 1-4See slide 13 for references. T 4

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