MaxCyte IPO Presentation Deck

Significant Increase in Both Efficiency and Viability Over Competing Technologies A study completed at a leading academic institution in Japan showed improved knock-in (KI) efficiency and higher cell viability compared to a competing electroporation platform for the correction in induced pluripotent stem cells (iPSC). E Knock-in (Pstl) [%] sSODN [pg] July 2021 Customer generated data showed higher editing efficiency S691C (Pstl) knock-in efficiency 13 4D-Nucleofestor 0 MaxCyte F Knock-in (EstUI) [%] 10 G694A (BstUI) knock-in efficiency 0 SSODN [ug] 0 6.7 13 4D-Nucleofector 0 MaxCyte Relative cell number [%] CONFIDENTIAL 120 100 RNP SSODN Electroporation Higher cell viability compared to competing technology الأمم المال Source: Kagita et al, Efficient sSODN-Mediated Targeting by Avoiding Cellular Inhibitory RNAs through Precomplexed CRISPR-Cas9/sgRNA Ribonucleoprotein. Stem Cell Reports ISSCR. April 2021. 6.7 13.3 67 133 4D-Nucleofector + 6.7 13.3 6.7 13.3 MaxCyte M MaxCyte

View entire presentation