Orthofix Investor Presentation Deck

Complementary High Growth Portfolio $7B of Focused High-Growth Market Segments* | 6.1% CAGR Spinal Implants Motion Preservation Spinal Fixation Biologics Cellular Allograft Lyograft Demineralized Bone Matrices Synthetic Bone Grafts Full Continuum of Care G Enabling Technologies Machine-vision 7D FLASH™ Navigation Orthopedics Limb Reconstruction Deformity Correction *SmartTRAK® 2022 2026 U.S. Estimates Focused growth segments include Enabling Technologies, Motion Preservation, Interbody, DBM, LLIF/OLIF, MIS and Long Bone Stimulation ©2023 Orthofix Medical Inc. All rights reserved | 5 Bone Growth Therapies Bone Growth Stimulation Non-Surgical Alternative Regenerative Technology ORTHOFIX® SeaSpine.

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