Cboe Results Presentation Deck

2021 Revenue Guidance +4-6% Net Revenue Contribution From Recent Acquisitions +6-7% Recurring Non-Transactional Organic Revenue Growth Cboe For 2021, expecting net revenue contribution from recent acquisitions in a range of 4 to 6 percentage points Leverage the deals closed in 2020 to accelerate organic growth in 2021 Targeting 6-7% organic growth from recurring non-transactional revenue Growth in subscribers expected to be key driver of organic recurring non-transactional revenue 12

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