BenevolentAI Investor Day Presentation Deck

TECH APPROACH Triage targets to select only the most promising hypotheses PREDICT TRIAGE TPA ASSAY A Programs / ALS Demo / ALS / ALS Search Q Target Symbol Filter Triage status Triaged (0) Assessment decision Match (0) Uncertain (220) Context Mechanism On other lists Present 1 Ligandability Triage criteria Biological Rationale 1 Safety Not triaged (250) 1 Not match (30) Clear all Absent Sort by: Target Rank ↑ ALS Prediction MAPKAPK2 MAPK activated protein kinase 2 Biological Rationale-class 1 (out of 4) MAPK7 Not Match Your comment (can be edited when changing target decision) Biological Rationale-class 2 (out of 4) DYRK1A mitogen-activated protein kinase 7 Not Match Ligandability-class 4 (out of 4) Biological Rationale - class 2 (out of 4) LDHA Uncertain Your comment (can be edited when changing target decision) Ligandability-class 4 (out of 4) Biological Rationale-class 3 (out of 4) 2 Target Rank? 1 Target Rank? dual specificity tyrosine phosphorylation regulated kinase 1A Ligandability-class 4 (out of 4) lactate dehydrogenase A Safety-class 1 (out of 4) 4 Target Rank ? Safety-class 3 (out of 4) Your comment (can be edited when changing target decision) Ligandability-class 4 (out of 4) Safety-class 1 (out of 4) Safety-class 3 (out of 4) Uncertain Your comment (can be edited when changing target decision) Therapeutic Evidence-class 3 (out of 3) 3 Target Rank ? Therapeutic Evidence-class 3 (out of 3) Therapeutic Evidence- class 3 (out of 3) Therapeutic Evidence-class 3 (out of 3) View from the Triage Tool Visualise Show criteria Chemical Opportunity-class 1 (out of 4) Chemical Opportunity-class 1 (out of 4) Chemical Opportunity-class 1 (out of 4) Chemical Opportunity-class 1 (out of 4) Copy UUIDS Showing 250 of 250 targets □ 2. Target ID G Benevolent 36

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