Pershing Square Activist Presentation Deck
Limited Project Level R&D Guidance
While the sales potential from Allergan's R&D pipeline remains
opaque, peers such as Astra Zeneca give more detailed disclosure:
Oncology
RIA
CVMD
MEDI4736
(incl.combination -$6.5bn
therapies)
AZD9291
(monotherapy)
Olaparb
PT003
PT010
Benralizumab
Non-Risk
Adjusted
PYS
Potential
Saxa/Dapa FDC
Source: Astra Zeneca May 2014 investor presentation
-$3bn
-$2bn
-$4bn
-$2bn
-$3bn
Non-Risk
Adjusted
Analyst PYS
Range
$2bn-$7bn
$1bn-$2bn
$1.5bn-$3bn
$3.5bn-$4bn
$1bn-$2bn
Key Dates Advantage
Q2:14
(Phl data)
65
02:14
(Phl data)
3 Oct 14
(PDUFA
date)
01:15
(Phill results)
2015
(Phill start)
02:14
(Phil date)
Q2:14
(Phill data)
• Potential first-to-market PD-L1 in Stage III NSCLC
following chemoradiation
Novel targeted mechanism of action with breakthrough
therapy designation
Potential first to market PARP inhibitor
.
• Potential first-in-class LABAILAMA in COPD in a pMDI
Triple therapy in development for both COPD and
Asthma
Anti-IL-SR with potential best-in-class efficacy for
eosinophil depletion
. Fixed dose combination with potential to develop
triple combination
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