Avantor Results Presentation Deck

1 Core Organic Growth & Adjusted EBITDA (Quarterly) USD in millions Total Avantor, Global GAAP consolidated net sales Core organic growth (decline) COVID Impact Organic growth (decline) M&A Impact FX Impact Reported net sales growth (decline) GAAP gross profit Adjustments for Ritter & Masterflex¹ Adjusted gross profit (non-GAAP) GAAP SG&A expense Amortization Acquisition/Integration-related expenses? Purchase accounting adjustments Other stock-based compensation (expense) benefit Restructuring & severance charges Reserve for certain legal matters Impairment charges? Adjusted SG&A expense (non-GAAP) 2,3 Other reconciliation items Depreciation Loss on extinguishment of debt Net foreign currency loss (gain) from financing activities Total other adjustments Adjusted EBITDA (non-GAAP) Navantor™ 1Q22 $1,950 $ $130 (39) $91 117 (43) $165 1Q22 $ $690 $690 $383 (92) (4) 4 1 (2) $291 22 2 0 $24 % 7.3% -2.2% 5.1% 6.6% -2.5% 9.2% $423 % 35.4% 0.0% 35.4% 19.6% -4.7% -0.2% 0.2% 0.1% -0.1% 0.0% 0.0% 14.9% 1.1% 0.1% 0.0% 1.2% 21.7% $ $118 (75) $42 91 (81) $52 2Q22 $1,911 2Q22 $ $648 (14) $662 0 (1) % 6.4% -4.1% 2.3% 4.9% -4.4% 2.8% $281 $352 18.4% (68) -3.5% (3) -0.2% 0.0% 0.0% 0.0% 0.0% 0.0% 14.7% 22 6 1 $29 % 33.9% -0.7% 34.6% 1.1% 0.3% 0.0% 1.5% $404 21.2% 3Q22 $1,857 $ $141 (59) $82 47 (107) $22 3Q22 $ $651 % 7.8% -3.3% 4.5% 2.5% -5.8% 1.2% 35.0% 0.0% $651 35.0% 2 (1) % $375 20.2% (80) -4.3% (6) -0.3% 0.0% 0.1% 21 3 (1) $23 -0.1% 0.0% 0.0% $289 15.6% 1.1% 0.2% -0.1% 1.2% $384 20.7% 4Q22 $1,795 $ % $52 2.7% (92) -4.8% ($40) -2.1% 14 0.7% (87) -4.5% ($113) -5.9% 4Q22 $ $615 (1) $615 $363 (79) (5) 0 $279 22 2 7 $31 $360 % 34.2% 0.0% 34.3% 20.2% -4.4% -0.3% 0.0% 0.0% 0.0% 0.0% 0.0% 15.6% 1.2% 0.1% 0.4% 1.7% 20.0% 1Q23 $1,780 $ % ($35) -1.8% (93) -4.8% ($128) -6.6% 0.0% -2.1% -8.7% (42) ($170) 1Q23 $ $625 $625 $394 (78) (9) (0) (5) $302 23 2 (0) $25 % 35.1% 0.0% 35.1% 22.1% -4.4% -0.5% 0.0% 0.0% -0.3% 0.0% 0.0% 16.9% 1.3% 0.1% 0.0% 1.4% $346 19.4% 2Q23 $1,744 % $ ($124) -6.5% (50) -2.6% ($174) -9.1% 0.0% 0.4% -8.7% 8 ($167) 2Q23 $ $590 33.8% 0.0% $590 33.8% $518 (79) 1 0 (7) (1) (161) $271 24 2 (2) $24 % $343 29.7% -4.5% 0.0% 0.0% 0.0% -0.4% -0.1% -9.2% 15.5% 1.4% 0.1% -0.1% 1.4% 19.7% 3Q23 $1,720 $ % ($147) -7.9% (32) -1.7% ($178) -9.6% 0.0% 2.3% 42 ($136) -7.3% 3Q23 $ $579 33.6% 0.0% 33.6% $579 $368 (75) (0) (0) (6) (3) $284 23 2 (1) $24 $318 % 21.4% -4.4% 0.0% 0.0% 0.0% -0.4% -0.2% 0.0% 16.5% 1.3% 0.1% 0.0% 1.4% 18.5% 4

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