Orthofix Investor Presentation Deck

2021 Revenue Mix SPINAL IMPLANTS Spine Fixation Motion Preservation 25% ● 23% $464M 14% YoY Growth 52% BIOLOGICS & REGENERATIVE TECHNOLOGIES Bone Growth Therapies - clinical Biologic Therapies - surgical LIMB RECONSTRUCTION & DEFORMITY CORRECTION Pediatric Charcot Foot ● ● ● Post-Traumatic REVENUE BY GEOGRAPHY 22% U.S. 78% International ORTHOFIX 18

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