BioNTech Investor Day Presentation Deck

Malaria, tuberculosis, and HIV remain endemic Malaria ~229 million cases in 2020 across the WHO Africa Region 601,000 deaths in 2020 in the WHO African Region (80% in children <5 years) Tuberculosis 10 million cases globally in 2020 1.5 million deaths globally in 2020 HIV, human immunodeficiency virus; WHO, World Health Organization. World Health Organization fact sheets. https://www.who.int/news-room/fact-sheets (accessed June 09, 2022). HIV [DAN Pandemic prep. 37.7 million living with HIV (of whom 2/3 in the WHO Africa Region) 680,000 deaths globally from HIV-related causes in 2020 CAR BIONTECH 82

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