AMD Results Presentation Deck

26 APPENDICES Reconciliation of GAAP to Non-GAAP Gross Profit and Gross Margin (Millions) GAAP gross profit GAAP gross margin % Stock-based compensation Non-GAAP gross profit Non-GAAP gross margin % (Millions) GAAP operating expenses GAAP Operating Expenses/Revenue % Stock-based compensation Acquisition-related costs. Non-GAAP operating expenses Non-GAAP Operating Expenses/Revenue % SA Q4 AND FY 2021 FINANCIAL RESULTS FEBRUARY 1, 2022 Reconciliation of GAAP to Non-GAAP Operating Expenses $ $ EA 2021 Q1'20 Q2'20 Q3'20 Q4'20 Q1'21 Q2'21 Q3'21 Q4'21 2020 818 $ 848 $ 1,230 $ 1,451 $ 1,587 $ 1,830 $2,086 $ 2,426 $ 4,347 $ 7,929 50% 45% 48% 46% 44% 45% 46% 48% 48% 44% 2 1 2 1 2 1 1 5 1 $1,231 $ 1,452 $ 1,588 $ 1,832 45% 6 $2,087 $ 2,427 $ 4,353 $ 7,934 820 $ 850 46% 44% 44% 46% 48% 48% 45% 50% 48% $ $ SA Q4'21 2021 2020 Q4'20 Q3'21 1,223 $ 881 $ 1,141 $ 4,293 $ 2,978 25% 27% 26% 26% 31% 111 78 98 374 268 9 14 8 42 14 789 1,035 $ 3,877 $ 2,696 24% 24% 24% 28% 1,103 $ 23% $ AMD

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