AMD Results Presentation Deck

17 Q4 2021 SUMMARY P&L - NON-GAAP¹ ($ in millions, except per share data) Revenue Gross Profit Gross Margin % Operating Expenses Operating Expense/Revenue % Operating Income Operating Margin % Net Income Earnings Per Share¹ Q4 AND FY 2021 FINANCIAL RESULTS FEBRUARY 1, 2022 Q4'21 $4,826 $2,427 50% $1,103 23% $1,328 27% $1,122 $0.92 Q4'20 $3,244 $1.452 45% $789 24% $663 20% $636 $0.52 1. Y/Y Up 49% Up 67% Up 560bps Up 40% Down 1pp Up 100% Up 7pp Up 76% Up 77% Q3'21 $4,313 $2,087 48% $1,035 24% $1,055 24% $893 $0.73 Q/Q Up 12% Up 16% Up 190bps Up 7% Down 1pp Up 26% Up 3pp Up 26% Up 26% Includes a higher tax rate beginning in Q1 2021. See Appendices for GAAP to Non-GAAP reconciliation and share count reference AMD

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