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Talkspace Investor Conference Presentation Deck

Effectiveness demonstrated with strong clinical outcomes Demonstrated improvements with asynchronous messaging therapy 10K+ individuals participated across 50 states 12 Weeks of asynchronous messaging therapy 67% Resulted in remission or improvement of symptoms on measures of depression and anxiety Hall BMC Psychiatry (2020) 20:20 https://doi.org/10.1186/s12888-020-02721- RESEARCH ARTICLE JOURNAL OF MEDICAL INTERNET RESEARCH Original Paper Two-way messaging therapy for depression and anxiety: longitudinal response trajectories Matt NYL Colu Talk Sum Duk Message Delivery for the Treatment of Posttraumatic Stress Disorder: Longitudinal Observational Study of Symptom Trajectories these Corr Math NYL One New Uniti Phon Emai Ab: BMC Psychiatry Back as aw to tru exam Obje acun Open Access 16 vodov Journal of Technology in Behavioral Science https://doi.org/10.1007/941347-018-0054-4 Malgaroli et al. The Effect of Messaging Therapy for Depression and Anxiety on Employee Productivity Meghan DellaCrosse¹ @Kush Mahan². Thomas D. Hull' Mark Springer international Publishing AG part of Springer Nature 2018 Abstract The World Health Organization estimates that more than 300 million people suffer from depression worldwide, and mental and behavioral disorders top the list of the leading categories of diseases and disorders in the USA, coming in second only to cardio- vascular disease. Such impact is seen to disproportionately affect the workplace since over 70% of those diagnosed with depression are also employed. Past research has suggested that employee absenteeism can be reduced through treatment for depression and anxiety, yet no study to date has examined the effectiveness of text therapy as a scalable delivery medium. Employing a retrospective within-subjects design, this study evaluated the treatment outcomes of text therapy for depression and anxiety and the impact such treatment had on engagement with employment. Adults secking text therapy treatment for a variety of disorders were recruited from a text therapy service (N=51) Clinical outcomes were measured using the Patient Health Questionnaire-9 and the Generalized Anxiety Disorder-2 after 14 to 15 weeks of treatment. An additional outcome variable was measured with the Work Productivity and Activity Impairment scale. Treatment acceptability was assessed with ratings of cost-effectiveness and retum on investment concerning increased employee productivity. Participants reported significantly less depression and anxiety (PHQ-9, d=1J4; and GAD-2, d. 1.17) on 7) overall. Thirty-one of the 38 participants (84%) with clinically elevated depression and 25 of the 39 participants (64%) with clinically elevated anxiety experienced clinically significant symptom reduction. Participants reported Healthcare workers benefited during COVID-19 pandemic 820 Healthcare workers participated 35% first time in therapy 56% Resulted in remission or improvement of symptoms on measures of depression and anxiety with just 30 days of care in most cases talkspace 12
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