BenevolentAI Investor Day Presentation Deck slide image

BenevolentAI Investor Day Presentation Deck

Colon biopsy signatures pixel intensity (AU) pixel intensity (AU) Phosphorylation pattern in... 2000 1800 1600 1400 1200 1000 800 600 400 200 0 20 SENER EGFRIEDB1 2000 1800 1600 1400 1200 1000 800 600 400 200 0 BR2/E82 EGFRBt81 ER2/ErbB2 FGFR1 FGFR1 FGFR3 FGFR3 FGFR4 FGFR4 InsR IGF-IR TrkA/NTRK1 TKB/NTRK2 MetHGFR Ron MSTIR InsR IGF-IR Tik A/NTRK1 MetHGFR TikB/NTRK2 Ron/MSTIR Ret ALOGFR ALK CKISCER Healthy colon biopsies PDGFR kitSCFR の SAHIT M-CSFRICSF-1R EphA1 EphA2 PLT3/FK2 M-CSFRICSF-IR del EphA1 Inflamed Crohn's biopsies Eph43 Tyro3/Dik EphB1 VEGFR2 Aki/PKB/Rac Th308 e2/TEK Tyro3/Dek 42 MAK Tie2/TEK Akt/PKB/R PKB/Rac T RK1 S6bos. Protein 0 AktPKB/Rac Ser473 D44/42 MAPK (ERK1/2) 96 dbos. Protein IRS-1 Zap-70 d healthy- healthy Stat3 Stat1 Lck Src -Zap-70 IAS-1 c-Abl S6 ribos. Protein p44/42 MAPK (EAK 1/2) Akt/PKB/Rac Ser473 Akt/PKB/Rac Thr308 -VEGFR2/KDA Tie2/TEK HeaTE Axl -Tyro3/Dtk -EphB4 EphB3 -EphB1 Spro EphA3 EphA2 Pu -EphA1 MCSE M-CSFR/CSF-1A FLT3/FIK2 c-kit/SCFA PDGFR ALK 2 Rot Ron/MSTIR MovHGFA TrkB/NTAK2 -TrkA/NTRK1 IGE-IR INSH InsA LEGFR4 FGFR3 FGFA1 HER3/ErbB3 HER2/ErbB2 -EGFA/ErbB 1 56 Benevolent 54
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