Bionomics IPO Presentation Deck

BNC210 Observed to Significantly Reduce Panic Symptoms in Humans: CCK-4-Induced Model Placebo- controlled study in 15 healthy volunteers who experienced a CCK-4-induced panic attack Bionomics Panic Symptom Scale (% of Placebo) 100 90 80 70 40 30 20 10 Total # of Panic Symptoms I -37.7% (p<0.048) CCR-4 = Cholecystokinin Tetrapeptide (o peptide that induces anxiety and panic symptoms) Panic Symptom Scale (% of Placebo) Placebo 100 90 70 60 50 30 20 10 Panic Symptom Intensity BNC210 -52.7% (p<0.041) BNC210 demonstrated statistically significant reduction in both number and intensity of panic symptoms measured with the Panic Symptom Scale 11

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