Renal Care 2022 Investor Conference

Global Market Expected To Grow ~4% Through 2025 ~$14B ~$3.5B ~$10.5B 2022E CAGR ~4% Peritoneal Dialysis (PD) ~6% Hemodialysis (HD)¹ -3% Baxter 2022 Investor Conference ~$16B ~$4.3B ~$11.5B 2025E Market Dynamics Opportunities Substantial shift globally to home dialysis driven by: o Accelerating patient preference to conduct therapy at home, rise in telemedicine & innovation of connected health solutions o New policies incentivizing innovation and shift to home (e.g., AAKHI, TPNIES) Challenges Significant near-term adverse mortality impact on overall dialysis patient population ¹Includes hemodialysis performed in-center and at home. 107

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