Evotec Investor Day Presentation Deck

evotec mAb 1 PAGE 94 MOLECULE DISCOVERY J.DISCOVERY™ mAb1 variant aggregate reduction and yield improved by 60% by resistance to low pH (3.3) aggregation Dramatic improvement in low pH aggregation achieved through optimised molecular design with Abacus Sequence optimisation improves manufacturability and yield 40.0 mAb 1 MOLECULE DESIGN J.MD" 3.6 mAb1 optimised. Kerwin et al. 2019 J Pharm Sci (In Press) PROCESS & PRODUCT DESIGN JP3 mAb2 3.4 mAb2 optimised. MANUFACTURING DESIGN J.PODⓇ m Ab2 mAb2 variant aggregate reduction and yield improved. by 700% by resistance to low pH (3.3) aggregation

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