Akouos IPO Presentation Deck

The Akouos Precision Genetic Medicine Platform 14 Novel Delivery Approach Proprietary AAV Vector Library CONFIDENTIAL Multimodal Capabilities AKOUOS Gene transfer targeting loss-of- function mutations Gene knockdown or editing targeting toxic gain-of-function or dominant negative mutations Therapeutic protein expression (e.g., monoclonal antibody) targeting disease pathways responsible for non-monogenic hearing loss

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