Genelux Investor Presentation Deck
Demonstrated Deep and Durable Tumor Shrinkage
Tumor Shrinkage
Key Clinical Takeaways
Refractory patients
performed as well as resistant
patients
Tumor Shrinkage
Overall, 86% of PRROC patients
showed tumor reduction, with
91% of Platinum-refractory
patients showing tumor reduction
ā
Four patients had 100% reduction
target lesions (two with
confirmed CR), including two
platinum-refractory patients
Duration of Response (DOR)
DOR of 7.6 Months in all platinum-
ā
Resistant patients
DOR of 8.0 Months in platinum-
refractory patients
GENELUX
Best change of target lesions from
baseline (%)
60
Change of target lesion size (%
change of SLD)
40
20
O
-20
-40
-60
-80
-100
15A-18
33
15B-09
15B-19
120
15A-19
15A-27
32
180
100
80
60
40
20
0
-20
-40 -30% partial response
-60
-80
-100
Duration of Response
15A-38
15B-18
platinum-resistant
platinum-refractory
240
15A-06
Time (days)
300
15A-30
15A-23
15B-01
15A-29
15A-05
70
360
15A-37
15B-17
PD
SD
15A-22
Objective Response
(CR or PR)
420
-30% partial response
15A-16
24 58 81 62 132 19
48
46 45
Baseline tumor burden as Sum of Longest Diameter of target lesions (mm)
65
15A-09
480
15A-25
83
15B-15
540
82
15A-31
12
15A-34
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