Company Overview
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Strategic composition of dronabinol and acetazolamide makes
IHL-42X an exciting novel potential treatment for OSA.
Dronabinol
Synthetic form of (-)-trans-49-
tetrahydrocannabinol (THC).
Approved in US for treatment of HIV/AIDS
induced anorexia and chemotherapy induced
nausea and vomiting.
Dampens afferent vagal feedback, stabilizes
respiratory patterns and dilates upper airway.
Two clinical trials to demonstrate effectiveness
in reducing AHI in patients with OSA.
Incannex
IHL-42X
Better outcomes,
lower doses
d AHI to greater extent than Acetazolamide and Dronabinol as
50.7% reduction
Avg. AHI
(up to 91.5% in clinical trials)
Acetazolamide
Carbonic anhydrase inhibitor.
Used to treat glaucoma, altitude sickness,
epilepsy and other indications.
Increases the difference between prevailing
PCO, and apnoeic PCO₂.
Demonstrated as an effective treatment for
OSA in 14 clinical studies.
Investor Presentation
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