Antofagasta Investor Update

Safety and health Our top priority A fatality after 33 months 49561 High Potential Incidents decreased by 24% Safety performance: Fatalities, HPI and LTIFR 316 Antofagasta plc | 2022 BofA Global Metals, Mining & Steel Conference 1.53 2017 1 1.59 1 2018 217 1.01 86 0.86 65 1.34 1 2019 2020 2021 Fatalities 1 Lost Time Injury Frequency Rate (LTIFR)* High Potential Incidents (HPI) LTIFR: the number of lost time injuries per 1 million hours worked 13 1.06 Q1 2022 4

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