G Medical Innovations IPO Presentation Deck
IDENTIFYING AND TREATING AFIB EARLY IS CRITICAL TO ACHIEVING
BETTER OUTCOMES FOR PATIENTS, PROVIDERS AND PAYERS
Admission
Probability of Survival Free
of Hospital
1.0
0.9-
0.8-
0.7-
0.6-
0.5-
0.4-
0.3-
0.2-
Hazard ratio, 0.62 (95% CI, 0.43-0.87)
P-0.007 by Cox regression
0.1- P-0.006 by log-rank test
0.04
0
12
24
36
Months of Follow-up
outcomes
Ablation
Medical therapy
48
60
Early rhythm-control therapy
associated with a lower risk of
adverse cardiovascular
1. Andrade J, NEIM 2021, 2. Kirchhoff P, NEIM 2021. 3. Marrouche NF, NEJM 2018
Incidence of death from
cardiovascular causes, stroke,
or hospitalization reduced with
early rhythm control
Cumulative Incidence (%)
80-
70-
60-
50-
40-
30-
20-
10-
0-
0
HR 0.79 (95% CI 0.66-0.84,
p = 0.005)
Usual care
Early rhythm control
Years since Randomization
Percent of Patients Free
from Recurrence
100-
80-
60-
40-
20-
Hazard ratio, 0.48 (95% CI, 0.35-0.66)
P<0.001
Antiarrhythmic drug therapy
Follow-up (Months)
Ablation
10
12
Death or hospitalization for
worsening heart failure reduced
with catheter ablation for AFib
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