AbCellera Investor Presentation Deck

05 ENGINEER. EXPRESSION & BIOANALYTICS COPYRIGHT © ABCELLERA 34 COMBINE ANY TWO ANTIBODIES TO CREATE NATIVE BISPECIFICS. Example mutations at a heavy-light chain (Fab) interface: V₁ ........ VH mutation A CH STANDARD PARENTAL IgG's HI mutation B BISPECIFIC IgG mutation C 5 SOURCE SEARCH DECODE ANALYZE ENGINEER 3 protein-protein interfaces with 1 to 4 mutations per domain to ensure correct and stable pairing of multiple heavy (V₁ CH) and light (V₁ C₁) chains

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