ATAI Investor Day Presentation Deck
CIAS phase 2a result summary
Extension of prior clinical data to CIAS
Safe and well-tolerated in SZ population
Dose dependent, widespread qEEG changes across brain regions
EO - Increased alpha/ASI (middle & high doses), decreased beta (lowest dose)
●
●
●
●
EC - Observed elevations in resting state alpha, increased ASI, and decreased TBR
Suggesting a relaxed wakeful state without drowsiness at the mid to high dose levels
ERP data suggests some dose-dependent cognition relevant changes
Evidence of bell-shaped dose-response
HVLT-R immediate recall effect size = 0.44 (20 mg)
Symbol coding effect size -0.4-0.8
atai
LIFE SCIENCES
●
●
"Symbol coding response is at a level that would correlate with
better work/school performance" – Keith Nuechterlein
| 40View entire presentation