AstraZeneca Results Presentation Deck slide image

AstraZeneca Results Presentation Deck

Rare Disease Total Revenue ($m) Soliris 15% decrease at CER to $2,429m in 9M 2023 1,200 1,000 800 600 400 200 0 Q3 Q4 Q1 Q2 2021 Q2 2023 83 115 88 86 99 124 91 74 221 216 190 179 183 184 163 591 574 523 491 448 445 420 ☐EM 53 EROW 86 Europe 199 240 ■US 460 608 Q3 2022 117 71 63 84 111 107 174 104 Q4 Q1 Q3 Total Revenue ($m) Ultomiris 58% growth at CER to $2,141m in 9M 2023 900 800 700 600 500 400 300 200 100 0 Q3 Q4 2021 4 ■EM ☐EROW 5 56 ■ Europe 69 100 73 US Q1 Q2 Q3 Q4 2022 24 6 4 70 72 77 105 120 122 167 214 220 236 315 Due to rounding, the sum of a number of dollar values and percentages may not agree to totals. 45 Q3 2021 Total Revenue shows the numbers reported by AstraZeneca following the acquisition of Alexion, which completed on 21 July 2021. CER = constant exchange rates; EM = Emerging Markets; EROW = Established Rest of World. Q1 4 13 90 98 134 159 381 365 Q2 2023 17 17 110 131 152 184 434 445 Q3 Total Revenue ($m) 350 300 250 200 150 100 50 0 Strensiq 24% growth at CER to $847m in 9M 2023 Q3 Q4 2021 APPENDIX | 9M 2023 Product Performance ☐EM 4 6 ☐EROW 15 20 ■ Europe 16 20 US 124 173 Q1 Q2 Q3 Q4 Q1 Q2 2023 2022 9 8 9 19 19 19 19 21 18 161 193 192 10 15 9 19 21 19 21 224 205 22 21 248 Q3 5 21 22 237
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