BioAtla Results Presentation Deck
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Osteosarcoma: Phase 1 & 2 (1.8mg/kg; n=7) Change in Target Lesion and
Progression Free Survival
Week 0
PHASE 1/2 - Osteosarcoma
Change in target lesion from baseline (%)
week 6
Interim data- Data cut-off of April 28, 2022
week 12
week 18
week 24
Progression Free Survival Probability
1.0
0.8
0.6
0.4
0.2
0.0
Number at Risk
All Patients
0
7
1
7
2
4
All Patients
Progression-free Survival)
Events
n(%)
4(57.1)
4
3
5
Months from First Dose
2 1
1
Mecbotamab vedotin - BA3011
Median (mos)
(95% CI)
3.8 (1.2-NE)
1
bicatla
PFS 3mo
% (95% CI)
57.1 (17.2, 83.7)
7
0
Recent independent phase 2 study demonstrated placebo PFS rate
at 2 months for 1st and 2nd line metastatic osteosarcoma of ~0%
(www.thelancet.com/oncology Vol 20 January 2019)
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