Evotec Results Presentation Deck

Clinical Preclinical Discovery evotec PAGE 22 Ph3 Ph2 Ph1 Insomnia CC - P2X3 ND ND ALS ND ND 12 ND 11 ND 10 ND 9 ND 8 ND 7 ND 6 ND 5 ND 4 ND 3 ND 2 ND 1 Partnered Pipeline Neuroscience & Pain NP-P2X3 Pain ND ND 14 LDD 3 LDD 2 LDD 1 OAB-P2X3 ND 15 EVT Glaucoma EVT Fragile X EVT Canavan EVT Gaucher EVT RPE-P EVT iPSC Myelin EVT iPSC- ICT The iceberg of co-owned product opportunities is growing In total > 200 projects with big financial upside Cajal Neurosciences Aeovian ND Facio FSHD 1 Facio FSHD 2 Exscientia Psychiatry Exscientia ND 1 LAB282 N=3 Breast cancer EVT iPSC Dir. Diff. LAB150 N=1 Unpartnered Pipeline A2A EVT 801 10 LDD 5 LDD 4 Onco 4 Onco 3 Onco 2 Onco 1 EVT TargetFAP EVT FF-Ab 2 EVT FF-Ab 1 EVT MDSC-screen EVT/MF AlloMod 3 EVT/MF AlloMod 2 EVT/TMF AlloMod 1 Oncology EVT LAB301 4 EVT LAB301 3 EVT LAB301 2 EVT LAB301 1 EVT iTab EVT iM EVT iTgd EVT INK EVT/Indiv Lung c 3 EVT/Indiv Lung c 2 EVT/Indiv Lung c 1 Equity Pipeline EVT act EVT Ice EVT ObliTaim Carrick Breast Cancer Carrick CRPC Carrick TNBC Exscientia ND 2 Exscientia ND 3 Immunitas solid and hemat Immunitas IMT-073 Exscientia ND 4 Quantro ND Breakpoint ND 2 Breakpoint ND 1 Blacksmith ND Exscientia 101 Exscientia 102 Exscientia N=5 DarkBlue Therapeutics Autobahn Labs Immunitas ND OxVax LAB150 N=1 Metabolic Diseases ND 10 ND 9 ND 8 ND 7 ND 6 ND 5 ND 4 ND 3 ND 2 ND 1 Fibrosis LDD 7 LAB282 N=7 BRIDGES Pipeline LDD 6 QRbeta Encapsß EVT S460 QRbeta iBeta EVT Fibr. IBD 2 EVT Fibr. IBD 1 EVT TargetTF CDK/fibrosis EVT TargetTF Fibrosis EVT iCardiomyocyte EVT NephSyn EVT Nurture EVT QUOD EVT Neplex EVT HPP EVT Nurture TID 1 Eternygen NASH/Diabetes Neph Thera ND Topas T1D Topas PV LAB150 N=1 LAB282 N=2 EVT Nurture TID 4 EVT Nurture TID 3 EVT Nurture TID 2 *Also includes Women's Health, Respiratory projects The Equity Pipeline does not contain programs from EVT/partners that are not publically disclosed Inflammation & Immunology* Endo - P2X3 Endo ND 8 ND 8 ND 7 ND 6 ND 5 ND 4 ND 3 ND 2 ND 1 EVT ILR-23 Endo P2X7 Fibrocor IPF Topas Anti-drug IR Topas ND 2 Topas ND 1 Blacksmith ND Celmatix OS Celmatix PCOS Fibrocor Fibrosis Fibrocor CA Nephropathy Exscientia Respiratory Exscientia N=5 CureXsys ND Topas Pemphis vulgaris Topas Celiac disease Exscientia ND 5 LAB150 N=2 LAB282 N=5 Topas Uveitis/Cholangiti Virology HBV Covid-19 3 HBV-HBX HBV RNA HBV-HBc EBV 2 EBV 1 Flu 2 Flu 1 BKV Exscientia Covid-19 LAB282 N=2 Anti-bacterial Noso-502 Naphtamidine S Neopyrrolomy cins Tribe Carb-X Noso-2G Cystobactamid eAMR Staph persist RNA Pol HDT VMM Forge LpxC UTI Forge LpxC Lung Forge LpxC STD Forge DXR Forge IspF Forge RNAP Forge ThrS Forge ND Exscientia ND 6 LAB282 N=2 Global Health CHIK-V Malaria AP series Resorcinomyci n TB HTS TB Whole Cell HTS Natural product TB patDB Product screen

View entire presentation