3Q22 Investor Update

TOBACCO REVENUE & PROFIT BREAKDOWN Unit sales¹ Net revenue Gross profit Gross profit margin² 3Q 2022 1.6M $11.5M $636K 5.5% ■ Tobacco 3Q 2021 1.1M $7.8M $292K 3.7% Net revenue and gross margin expansion QoQ were primarily driven by: Volume increases in the number of cartons sold ■ Price increases Favorable mix, including export cigarettes ■ Change % 45% 48% 118% 180 bps 1. Tobacco unit sales volume is measure in cartons 2. Gross profit margin is calculated by dividing gross profit by net revenues 3. Contract manufacturing operations (CMO) Ž Opportunity for additional tobacco net revenue growth and margin expansion with: Increased sales volume of higher margin CMO cigarette customers 22ND CENTURY GROUP Accelerated VLNⓇ launch driving increased revenue and margin contribution from premium VLNⓇ products 19

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