Q1 2023 Earnings Presentation

APPENDIX Q1 2023 EBITDA [$M] Non-GAAP Net Income* GAAP Interest Expense, Net Non-GAAP Income Tax Provision GAAP Depreciation Expense Amortization Expense** Total Non-GAAP EBITDA Margin (% of revenue) Mar 31, 2023 $95.1 2.8 36.9 14.3 (0.1) 53.8 2023 Bruker $149.0 21.7% Mar 31, 2022 $74.6 3.9 36.5 12.2 (0.2) 52.4 $127.0 21.3% A +28% -28% +1% +17% +3% +17% *Attributable to Bruker. Sum of items may not total due to rounding. **GAAP depreciation and amortization, with purchased intangible amortization $10.7 million 2023 and $9.3 million 2022 is already adjusted out of non-GAAP net income. See slide 19. Q1 2023 Earnings Presentation | BRUKER May 4, 2023 I 23

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