ATAI Investor Day Presentation Deck

Acute bell-shaped cognitive response T-scores (Normalized for age, gender, and education level) atai LIFE SCIENCES 10 8 6 4 2 0 -2 -4 + HVLT I I I I 1 I I 1 I 1 1 I I I 1 I I I I I I I I I I I I i I I I ! Symbol Coding 10mg 20mg 40mg n=7 n=8 n=8 n=8 Category Fluency 80mg -I I "Symbol coding is the most sensitive measure and it correlates well with the other tasks in MATRICS" - Rich Keefe Improved Cohen's d* (Symbol Coding): 20 mg: 0.79 40 mg: 0.56 80 mg: 0.38 *Day 4 vs Day 2 | 38

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