Antofagasta Investor Conference Presentation Deck

Safety and health The safety and health of our people is our top priority 1 1.53 2017 316 1.59 1 2018 217 1.01 2019 86 0.86 2020 65 LTIFR: the number of lost time injuries per 1 million hours worked 1.34 Fatalities 1 Lost Time Injury Frequency Rate (LTIFR) ¹ High Potential Incidents (HPI) 1 2021 ● 2021 performance In July 2021 regrettably a contractor suffered a fatal accident in the open pit at Los Pelambres High Potential Incidents decreased by 24% COVID-19: high vaccination rate achieved (97%) Antofagasta plc | 2022 BMO Global Metals & Mining Conference 4

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