Orthofix Investor Presentation Deck

Orthofix Q4 and FY 2022 Highlights $460.7M Full Year 2022 Revenue 1.5% Increase YoY at Constant Currency 24% 23% Spinal Implants Limb Reconstruction & Deformity Correction 53% Biologics & Regenerative Technologies Revenue Mix 78% 22% Geography Mix U.S. International ©2023 Orthofix Medical Inc. All rights reserved | 15. $122.2M Q4 2022 Revenue Flat YoY at Constant Currency $50.7M Cash & Cash Equivalents, 12/31/2022 No Borrowings under credit facility $30M borrowed on 01/03/2023 $48.6M Full Year 2022 Adjusted EBITDA 10.5% as Percent of Revenue ORTHOFIX®Ⓡ SeaSpine

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