Taysha IPO Presentation Deck

Well capitalized to advance robust pipeline with strong investor syndicate ~$126M gross proceeds raised since company formation ~$118M cash and cash equivalents* *As of June 30, 2020, after giving effect to the receipt of $107.1 million in proceeds from the sale and issuance of Series A and Series B convertible preferred stock in July and August 2020 Premier syndicate of long-term, life science investors PBM CAPITAL Nolan Capital G/ INVUS Octagon Fidelity ETHIN ARROWMARK CASDIN PERCEPTIVE ADVISORS venrock FRANKLIN TEMPLETON SANDS CAPITAL Other institutional mutual fund investors

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