#1#2#3Kristin Peck Chief Executive Officer zoetis#4FIRST QUARTER FINANCIAL RESULTS Key Takeaways 1Q Revenue Growth and Earnings Results Generated 4% operational¹ revenue growth and a 3% operational decline in adjusted net income², with International revenue up 10% operationally, partially offset by a decline of 1% in the U.S. ● • Our livestock portfolio growth of 12% operationally was broad-based, with double-digit operational growth across cattle, poultry, sheep and fish. ● Companion animal revenue was flat operationally, with growth in our monoclonal antibodies for pain, Librela and Solensia, offsetting declines in Apoquel, parasiticides and anti-infectives. Maintains Guidance for 2023 • We are reaffirming our 2023 guidance provided during February's earnings call. ● Revenue range of $8.575B and $8.725B, with operational growth of 6% to 8%. Adjusted net income range of $2.490B and $2.540B, with operational growth of 7% to 9%. O O ● • We anticipate double-digit operational growth for companion animal products and relatively flat operational growth in our livestock portfolio in 2023. 4 ¹ Operational results (a non-GAAP financial measure) excludes the impact of foreign exchange. 2 Adjusted net income (a non-GAAP financial measure) is defined as reported GAAP net income, excluding purchase accounting adjustments, acquisition-related costs and certain significant items. zoetis#5Wetteny Joseph Executive Vice President and Chief Financial Officer zoetis#6FIRST QUARTER FINANCIAL RESULTS Income Statement Highlights Revenue Reported Net Income Reported Diluted Earnings Per Share Adjusted Net Income ¹ 2023* $2,000 6 552 $1.19 607 First Quarter $1.31 2022* $1,986 595 $1.26 625 Adjusted Diluted Earnings Per Share ¹,2 * Millions of dollars, except per share data 1 Adjusted net income and adjusted diluted earnings per share (non-GAAP financial measures) are defined as reported net income and reported diluted earnings per share, excluding purchase accounting adjustments, acquisition-related costs and certain significant items. 2 Adjusted diluted earnings per share decrease of 1% includes 0% foreign exchange impact, an operational decrease of 1%. Change 1% $1.32 (7)% (6)% (3)% (1)% zoetis#7#8#9#10#11#12#13#14#15