Bionomics Results Presentation Deck

Fast-Acting Tablet Formulation Well-Suited for Treating Acute Anxiety Disorders Desirable Solid-Dose PK Properties 2 1. No food effect 2. Rapid exposure 3. Dose-linear response 8 1| [BNC210] ng/ml 1750- 1500- 1250- 1000- 750 500 250- Novel tablet alleviates food effect 300 mg Tablet, Fasted 300 mg Tablet, High Fat Meal 1 1 T T 01234 6 8 10 12 Time (Hr) 18 20 24 2 Å O 45-105 minutes to reach maximum absorption concentrations across the dose range ✓ IP coverage extends to late 2030's with novel formulation 3| [BNC210] ng/ml Novel tablet has dose linear exposure 5000- 4000- 3000- 2000- 1000- 1200 mg -- 900 mg 600 mg 300 mg F T T 0 2 4 6 8 10 12 14 16 18 20 22 24 Time (Hr) Bionomics 0

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