Bionomics Results Presentation Deck

Clinical Meaningfulness: BNC210 Demonstrates Comparable Magnitude of Effect with Benzodiazepines Mean Change in SUDS Diazepam 5 mg* Mean SUDS Score 55 50 45 40 35 30 25 20 15 10 Diazepam Anticipation 1 2 Placebo Performance 3 17 *Adapted from Helmus et al. Experimental and Clinical Psychopharmacology, 2005 4 Mean CFB SUDS Score Mean Change from Baseline in SUDS BNC210 - Ph2 35- -BNC210 Overall - Placebo 30- 25- 20 15- 10- АО Anticipation A1 -2 A2 PO P1 Performance P2 P3 P4 P5 Bionomics 9

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