Ginkgo Results Presentation Deck

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Ginkgo

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ginkgo

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Healthcare

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August 2021

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#1Grow with Ginkgo H1 Revenue Update & Business Review August 18, 2021 H1 UPDATE | AUGUST 2021 GINKGO BIOWORKS#2DISCLAIMER Forward-Looking Statements This presentation contains certain forward-looking statements within the meaning of the federal securities laws, including statements with respect to the proposed business combination (the "Business Combination") between Ginkgo Bioworks, Inc. ("Ginkgo") and Soaring Eagle Acquisition Corp. ("Soaring Eagle"), including statements regarding the anticipated timing of the extraordinary general meeting of Soaring Eagle's shareholders (the "Special Meeting") and the consummation of the Business Combination, the services offered by Ginkgo and the markets in which it operates, and Ginkgo's projected future results These forward-looking statements generally are identified by the words "believe," "project," "expect," "anticipate," "estimate," "intend," "strategy," "future," "potential," "opportunity," "plan," "may," "should," "will," "would," "will be," "will continue," "will likely result," and similar expressions. Forward-looking statements are predictions, projections and other statements about future events that are based on current expectations and assumptions and, as a result, are subject to risks and uncertainties. Many factors could cause actual future events to differ materially from the forward-looking statements in this presentation, including but not limited to: (i) the risk that the transaction may not be completed in a timely manner or at all, which may adversely affect the price of Soaring Eagle's securities, (ii) the risk that the transaction may not be completed by Soaring Eagle's business combination deadline and the potential failure to obtain an extension of the business combination deadline if sought by Soaring Eagle, (iii) the failure to satisfy the conditions to the consummation of the transaction, including the adoption of the agreement and plan of merger by the shareholders of Soaring Eagle and Ginkgo, the satisfaction of the minimum trust account amount following redemptions by Soaring Eagle's public shareholders and the receipt of certain governmental and regulatory approvals, (iv) the lack of a third party valuation in determining whether or not to pursue the proposed transaction, (v) the occurrence of any event, change or other circumstance that could give rise to the termination of the agreement and plan of merger, (vi) the effect of the announcement or pendency of the transaction on Ginkgo business relationships, performance, and business generally, (vii) risks that the proposed transaction disrupts current plans of Ginkgo and potential difficulties in Ginkgo employee retention as a result of the proposed transaction, (viii) the outcome of any legal proceedings that may be instituted against Ginkgo or against Soaring Eagle related to the agreement and plan of merger or the proposed transaction, (ix) the ability to maintain the listing of Soaring Eagle's securities on Nasdaq, (x) volatility in the price of Soaring Eagle's securities due to a variety of factors, including changes in the competitive and highly regulated industries in which Ginkgo plans to operate, variations in performance across competitors, changes in laws and regulations affecting Ginkgo's business and changes in the combined capital structure, (xi) the ability to implement business plans, forecasts, and other expectations after the completion of the proposed transaction, and identify and realize additional opportunities, and (xii) the risk of downturns in demand for products using synthetic biology. The foregoing list of factors is not exhaustive. You should carefully consider the foregoing factors and the other risks and uncertainties described in the "Risk Factors"" section of the Proxy Statement (as defined below) and in Soaring Eagle's other filings with the Soaring Eagle. Soaring Eagle and Ginkgo caution that the foregoing list of factors is not exclusive. Soaring Eagle and Ginkgo caution readers not to place undue reliance upon any forward-looking statements, which speak only as of the date made. Neither Soaring Eagle nor Ginkgo undertake or accept any obligation or undertaking to release publicly any updates or revisions to any forward-looking statements to reflect any change in its expectations or any change in events, conditions or circumstances on which any such statement is based. Industry and Market Data In this presentation, Ginkgo relies on and refers to certain information and statistics regarding the markets and industries in which Ginkgo competes. Such information and statistics are based on Ginkgo's management's estimates and/or obtained from third-party sources, including reports by market research firms and company filings. While Ginkgo believes such third-party information is reliable, there can be no assurance as to the accuracy or completeness of the indicated information. Neither Ginkgo nor Soaring Eagle has independently verified the accuracy or completeness of the information provided by the third-party sources. Trademarks This presentation may contain trademarks, service marks, trade names and copyrights of other companies, which are the property of their respective owners, and Ginkgo's use thereof does not imply an affiliation with, or endorsement by, the owners of such trademarks, service marks, trade names and copyrights. Solely for convenience, some of the trademarks, service marks, trade names and copyrights referred to in this presentation may be listed without the TM, Ⓒ or Ⓡ symbols, but Ginkgo will assert, to the fullest extent under applicable law, the rights of the applicable owners, if any, to these trademarks, service marks, trade names and copyrights. Additional Information and Where to Find It This presentation relates to a proposed Business Combination between Ginkgo and Soaring Eagle. This presentation does not constitute an offer to sell or exchange, or the solicitation of an offer to buy or exchange, any securities, nor shall there be any sale of securities in any jurisdiction in which such offer, sale or exchange would be unlawful prior to registration or qualification under the securities laws of any such jurisdiction. In connection with the proposed transaction, Soaring Eagle filed a Proxy Statement on August 13, 2021 (the "Proxy Statement"). The Proxy Statement has been sent to all Soaring Eagle shareholders as of the Record Date. Soaring Eagle also will file other documents regarding the proposed transaction with the SEC. Before making any voting decision, investors and security holders of Soaring Eagle and Ginkgo are urged to read the Proxy Statement and all other relevant documents filed or that will be filed with the SEC in connection with the proposed transaction as they become available because they will contain important information about the proposed transaction. Investors and security holders may obtain free copies of the Proxy Statement and all other relevant documents filed or that will be filed with the SEC by Soaring Eagle through the website maintained by the SEC at www.sec.gov. In addition, the documents filed by Soaring Eagle may be obtained free of charge by written request to Soaring Eagle at 955 Fifth Avenue, New York, NY, 10075, Attention: Eli Baker, Chief Financial Officer, (310) 209-7280. Participants in Solicitation Soaring Eagle and Ginkgo and their respective directors and officers may be deemed to be participants in the solicitation of proxies from Soaring Eagle's shareholders in connection with the proposed transaction. Information about Soaring Eagle's directors and executive officers and their ownership of Soaring Eagle's securities is set forth in Soaring Eagle's filings with the SEC. To the extent that holdings of Soaring Eagle's securities have changed since the amounts printed in Soaring Eagle's Proxy Statement, such changes have been or will be reflected on Statements of Change in Ownership on Form 4 filed with the SEC. Additional information regarding the interests of those persons and other persons who may be deemed participants in the proposed transaction may be obtained by reading the Proxy Statement. You may obtain free copies of these documents as described in the preceding paragraph. 2#3Our Mission Make biology easier to engineer illa H1 UPDATE | AUGUST 2021 GINKGO BIOWORKS 3#4We believe... 1 Cell programming is starting to become mainstream. We have increased our 2021 outlook for number of new programs from 23 to 30 due to higher-than-expected inbound interest from potential customers and enhanced credibility from completing programs. 2 Downstream value will become more valuable than Foundry service revenue. Foundry service revenue de-risks platform investments, but "wins" come from successful programs. We've heard a lot of questions about how downstream value works so we're giving 3 near-term case studies. 3 Delta sucks. And so will the next thing. Biosecurity will be a new market separate from diagnostics and we are becoming a leader due to our initial K-12 testing offering. We are now expecting our revenue to be at least $75 million for the full year. H1 UPDATE | AUGUST 2021 GINKGO BIOWORKS 4#5Recent Highlights New Programs Program Successes Biosecurity +11 new programs in H1 CRONOS GROUP $400M+ CORTEVA™ motif FOODWORKS agriscience Biogen aldevron Kalo Other Highlights DUTCH DNA Announced acquisition of Dutch DNA (closed 7/1) a heartbeat ahead (+3 from existing customers) aldevron state contracts for K-12 testing 1,000+ schools served Reshma Kewalramani (CEO of Vertex) announces she will join Board of Directors (1) Biosecurity contract value and performance is subject to Ginkgo's ability to conduct sufficient outreach to school districts, school adoption rates of Concentric and the volume of testing performed within contracted states. These state contracts can be paused or terminated early and there is significant uncertainty in the K-12 testing market in general as the facts and circumstances of the pandemic change regularly. H1 UPDATE | AUGUST 2021 GINKGO BIOWORKS 5#6AGENDA H1 Revenue Update & Full Year Outlook Investor Presentation Supplement The Market for Cell Programming Downstream Value and Program Updates Biosecurity Q&A H 1 UPDATE | AUGUST 2021 GINKGO BIOWORKS 6#7AGENDA H1 Revenue Update & Full Year Outlook Investor Presentation Supplement Q&A H 1 UPDATE | AUGUST 2021 GINKGO BIOWORKS 7#8H1 Revenue Update $Ms New Programs Launched GAAP Revenue: Foundry Biosecurity Total Revenue FY 2020 18 $59 $17 $77 (Unaudited) 6mo ended June 30, 2020 9 $31 $31 2021 11 $44 $44 $88 % YoY 22% 41% NM 180% H 1 UPDATE | AUGUST 2021 GINKGO BIOWORKS 8#9Full Year Outlook $Ms New Programs Launched GAAP Revenue: Foundry Biosecurity (1) Total Revenue FY 2020 18 $59 $17 $77 (Unaudited) 6mo ended June 30, 2020 9 $31 $31 2021 11 $44 $44 $88 % YoY 22% 41% NM 180% 2021 FY Outlook Original 23 $100 $50 $150 Updated 30 $100 $75+ $175+ In 2021 Outlook 30% 50%+ % Change 17%+ 2021 Updated vs. 2020A 67% 69% NM 127%+ Plus: we expect to see downstream value for certain programs delivered or nearing completion in H2 2021 (1) Biosecurity contract value and performance is subject to Ginkgo's ability to conduct sufficient outreach to school districts, school adoption rates of Concentric and the volume of testing performed within contracted states. These state contracts can be paused or terminated early and there is significant uncertainty in the K-12 testing market in general as the facts and circumstances of the pandemic change regularly. H 1 UPDATE | AUGUST 2021 GINKGO BIOWORKS 9#10AGENDA H1 Revenue Update & Full Year Outlook Investor Presentation Supplement The Market for Cell Programming Downstream Value and Program Updates Biosecurity Q&A H 1 UPDATE | AUGUST 2021 GINKGO BIOWORKS 10#11Over 70 major customer programs across diverse industries have run on our platform through 2020 Cumulative Major 3rd Party Programs 80 60 40 20 0 PRE-2015: GOVERNMENT PROGRAMS First 5+ years of technology building funded through non-dilutive government programs (DARPA, SBIR, etc.) CONSUMER & TECHNOLOGY Early experimentation making fine chemicals for flavors & fragrances + INDUSTRIAL & ENVIRONMENT Experience in flavors & fragrances enabled expansion into industrial chemicals 2015 ■Consumer & Technology 2016 From May 2021 Investor Presentation Gaining traction within increasingly sophisticated end markets + AGRICULTURE Selection by Bayer for agriculture JV after significant industry vetting 2017 Industrial & Environment + FOOD & NUTRITION Motif (Louis Dreyfus and Fonterra) launches portfolio of animal-free protein programs Agriculture 2018 Food & Nutrition + PHARMA & BIOTECH Mammalian capabilities & Synlogic partnership 2019 Pharma & Biotech = DIVERSIFIED PLATFORM Can respond rapidly to emerging opportunities and global threats 2020 Gov't & Defense Note: "Major" programs exclude proof of concept work and ancillary projects and typically have at least $500K actual / expected development costs on behalf of a customer H1 UPDATE | AUGUST 2021 GINKGO BIOWORKS 11#12Programs drive both predictable near-term revenues and long-term value creation with asymmetric upside potential Foundry Upfront payments to cover R&D costs for customer programs Yr 1 Foundry Yr 2 Yr 3 Highly predictable revenue stream independent of program success From May 2021 Investor Presentation Note: Illustrative economics; variation exists between programs Yr 4 Royalty Stream Yr 5 Value sharing via customer equity and/or royalties on completed programs Yr 6 Downstream Value Yr 7 Yr 8 ... OR Equity Equity represents the risk- adjusted NPV of a potential royalty stream TI Yr 0 Yr 4 T I --1 I Yr 5 Yr 6 I I I I Yr 7 I 1 I Yr 8 ... Cash flows from value share are typically 100% contribution margin as Ginkgo incurs minimal ongoing support or delivery costs The choice to structure downstream economics as royalties or equity is typically based on customer size H 1 UPDATE | AUGUST 2021 GINKGO BIOWORKS 12#13Thus, Ginkgo taps into two distinct addressable markets: one for the R&D itself (Foundry Revenue) and one for the products enabled (Downstream Value) Existing market for cell engineering lab operations ($B) $60 $58B $50 $40 $30 $20 $10 Market for Cell Programming R&D $0 ■Cell Engineering Labor Cell Engineering Tools $28B $10 $17 2019 $33B $12 $21 2020E Source: Piper Sandler Research 20% CAGR $40B $15 $25 $48B $18 $30 $22 $36 From May 2021 Investor Presentation 2021E 2022E 2023E Ginkgo can tap into both labor and tools mkts: Our scale dramatically reduces costs We bring efficiency to scientists at the bench Emerging Market for Products Enabled Annual Direct Economic Impact By Domain - 2030-2040 (partial estimate) $1.2T $500B Health $1.2T $800B Food & Agriculture $700B $200B Consumer High Estimate Low Estimate + significant secondary effects not measured $300B $200B Materials & Energy $300B $100B Other Source: McKinsey Global Institute; The Bio Revolution: Innovations transforming economies, societies, and our lives (May 13, 2020) Note: these estimates reflect the estimated biotechnology penetration of these end-markets H1 UPDATE | AUGUST 2021 GINKGO BIOWORKS 13#14Ginkgo's credibility across end-markets is driving inbound interest and accelerating the pace of new program launches # of New Programs by Year 30 10 0 18 2020A %49+ 30 Prior Projection 11 in H1 2021E 19 New Programs Expected for H2 Increasing annual outlook from 23 to 30 Strong mix of new logos (-60%) & repeat customers (-40%) Pharma/biotech trending to approx. 35% of H2 programs Strong momentum with earlier-stage businesses 11 New Programs in H1 CORTEVA agriscience aldevron Biogen With 3 new programs from repeat customers Kalo Pharma & Biotech Food & Agriculture Industrial & Consumer Large market for cell programming R&D across segments Market Size (1) $15-$20B $5-$10B $7-$10B Mature Companies Organizational focus and benefit from incremental scale & codebase breadth Caldevron Biogen (1) Market size reflects management estimates for cell programming R&D by industry, excluding spending in academic research CORTEVA agriscience SUMITOMO CHEMICAL KERRY Cargill moderna ROBERTET ADM Roche Startups Leapfrog incumbents with Ginkgo's scale economics and reduce upfront capital investments needed synlogic Antheia Aj, AJINOMOTO B BAYER JOYN R BIO CRONOS GROUP motif FOODWORKS genomatica Kalo BOLT THREADS A ALLONNIA ( A ( Scale and efficiency of the platform wins; form close technical partnership and have opportunity to penetrate large existing R&D budgets Breadth of capabilities vs. in- house teams focused on plant biology/ food science; increasingly the default choice Recent success delivering commercial cell programs in these sectors is making Ginkgo the clear leader Once a customer is on the platform, Ginkgo's alliance management team works with the customer to identify new program areas. Repeat customers are expected to represent about a third of new programs annually. H 1 UPDATE | AUGUST 2021 GINKGO BIOWORKS 14#15AGENDA H1 Revenue Update & Full Year Outlook Investor Presentation Supplement The Market for Cell Programming Downstream Value and Program Updates Biosecurity Q&A H 1 UPDATE | AUGUST 2021 GINKGO BIOWORKS 15#16Diversity in downstream value structures, some being realized today Milestones Lump-sum payment upon the achievement of specified criteria Case studies generating value today: 1 CRONOS GROUP Ginkgo may unlock over $100M of milestones upon program completion and commercialization of all programs(1) Examples of other active programs: Biogen Up to $115M in milestone payments Royalties Royalties based on sales of end products (structures can vary: percent of revenue, cost of goods sold, etc.) Caldevron Roche Note: Illustrative economics; variation exists between programs (1) Value granted upon commercialization and achievement of technical milestones; actual value of shares depends on share price. Tiered royalty on sales based on efficiency of process; high end far exceeds typical rates in biopharma industry Tiered royalties up to double digits on sales 3 Equity Equity grants in new companies + benefit from appreciation driven by successful programs motif FOODWORKS JOYN BIO Ginkgo received Series A shares ($90M strategic round); value appreciated during Series B funding ($226M raised) Ginkgo owns approx. 35% of joint-venture with Bayer H1 UPDATE | AUGUST 2021 GINKGO BIOWORKS 16#17CASE STUDY 1 Ginkgo is developing 8 molecules for Cronos through two major programs, the first of which is expected to be commercialized this year CRONOS GROUP I ▪ Ginkgo Bioworks to design microorganisms which can produce desired "target cannabinoids" at an industrial scale ▪ 8 target cannabinoids to be produced by yeast via industrial fermentation ▪ Target production yields at a fraction of the cost of traditional cannabinoids production in plants: < $1,000 USD per KG Cronos Group will have the exclusive right to use and commercialize the key patented intellectual property related to the production of the target cannabinoids perpetually and globally CANNABINOID PRECURSORS NATURALLY OCCURRING IN PLANT DECARBOXYLATION Partnership Overview CBGA MAJOR CANNABINOIDS THCA CBDA CBCA Į THC Į ↓ CBD CBC CBGVA ✓ 1 THCVA CBDVA CBCVA Į THCV Program 1 Source: Cronos Group (FINAL Ginkgo Deal Announcement Presentation, September 4, 2018) ↓ CBDV Program 2 ↓ CBCV "At this stage, we have all the necessary licenses to commercialize a product using cultured cannabinoids produced in our Winnipeg facility and we plan to be the first to market with a product that leverages this technology in Canada later this year. We'll be using cultured CBG as our first product introduced to the market, enabled by our partnership with Ginkgo, and we expect the final productivity target for CBG will be achieved in the coming weeks prior to September 2021, as previously announced. We are making strides to ensure that Cronos become synonymous with innovation. Launching cultured rare cannabinoids as a broader long-term approach to branding and product differentiation." Partner (signed 2018) Program Goals Progress to Date Kurt Schmidt, President & CEO Cronos Q2 2021 Earnings Call (August 6, 2021) Collaboration in Brief Cronos Group, a publicly traded Canadian cannabis company Design microorganisms that can produce desired target cannabinoids through industrial-scale fermentation Cronos has announced commercial production and upcoming market launch of CBG (first of 8 molecules) H1 UPDATE | AUGUST 2021 GINKGO BIOWORKS 17#18Cronos programs contribute both Foundry Revenue and Equity-Based Commercial Milestones Foundry Revenue ($M) $22M total Foundry Revenue budgeted across 2 major programs (life of program revenues) $25 $20 $15 $10 $5 Foundry $0 $10M $12M+ (1) R&D Milestones Foundry Access Fee Program Active Program #1: CBG(A) At Commercialization CBC(A) In Development CBD(A) THC(A) In Development In Development Stage Active Program #2: CBGV(A) CBCV(A) CBDV(A) THCV(A) Downstream Value In Development In Development In Development Development In Equity Milestones - # of Cronos Shares 1,467,490 1,467,490 2,201,236 2,934,981 1,467,490 1,467,490 1,467,490 2,201,236 1) Foundry Access Fee is a fixed amount paid quarterly; the total amount therefore depends on the length of the program(s). 2) Source: Cronos Q2 2021 earnings call. 3) Value granted upon commercialization and achievement of technical milestones, expected this year; actual value of shares depends on share price. Stock price calculated as of close of market 8/17/2021. CASE STUDY 1 CRONOS GROUP Cronos has reported they expect to grant Ginkgo these shares in 2021 as part of this program. (2) Shares are valued at approximately $9M at the current share price.(3) H1 UPDATE | AUGUST 2021 GINKGO BIOWORKS 18#19New partnership with Aldevron has potential to generate substantial near-term royalties mRNA Supply Chain is Expanding for Moderna and Pfizer/BioNTech have paved the way future mRNA therapeutic growth Modality yields faster time to market and strong performance Pfizer + Moderna are expected to produce 4-6 billion doses annually for COVID-19 ● ● Large pipeline of population-scale mRNA vaccines in development (e.g. COVID boosters, flu) mRNA supply chain requires investment Prior to COVID, mRNA modality was experimental and generally being directed to relatively rare diseases Several key components (pDNA, processing enzymes, even freezers, etc.) have become bottlenecked ● Aldevron collaboration dramatically improves availability and cost of Vaccinia Capping Enzyme (VCE), enabling it to be used in support of more therapies and doses New COVID Vaccines Need Absurd Amounts of Material and Labor SCIENTIFIC AMERICAN MEDICINE Companies are scrambling to obtain supplies for hundreds of millions of doses of a type of vaccine that has never been made at this scale before By Charles Schmidt on January 4, 2021 Partner (signed 2021) Program Goals CASE STUDY 2 aldevron Progress to Date Collaboration in Brief Aldevron, a leading manufacturer of nucleic acids and proteins, serving the biotechnology industry. Recently announced pending acquisition by Danaher for $9.5Bn. Engineer organism and create new manufacturing process to improve production volumes and cost of Vaccinia Capping Enzyme (VCE), a key reagent for certain mRNA vaccines Completed program and yielded >10x improvement in process, Aldevron is in the market with novel product H1 UPDATE | AUGUST 2021 GINKGO BIOWORKS 19#20New partnership with Aldevron has potential to generate substantial near-term royalties Foundry Ginkgo conducted VCE R&D work pro-bono upon discovering supply chain. bottlenecks as part of COVID-19 response programs + Downstream Value CASE STUDY 2 aldevron Ginkgo receives a royalty on sales, in a tiered structure with rates increasing as process improvements are achieved. With breakthrough process improvements, the royalty rates are meaningful and far exceed typical rates in the biopharma industry. Aldevron expects to begin selling product in 2021 and as mRNA modalities continue to grow, program has potential to generate strong recurring revenues. H1 UPDATE | AUGUST 2021 GINKGO BIOWORKS 20#21Motif FoodWorks, which has a multi-program collaboration with Ginkgo, launching first major products this year The Boston Globe Ginkgo's spinout Motif to release plant-based meat tech after raising $226 million By Anissa Gardizy Globe Staff, Updated June 16, 2021, 8:28 a.m. D The Motif FoodWorks food science lab. MOTIF FOODWORKS The plant-based food startup that spun out of Ginkgo Bioworks is getting ready to unveil its first product. Boston's Motif FoodWorks, with $226 million in new funding, announced on Wednesday that it plans to release food technology designed to improve the taste and aroma of meat alternatives by the end of the year. Another 'uct designed to add texture and juiciness to fake meat is expected to be available next year. Number Active Programs 2018 Meat Alternatives Ground Applications, Snacks Rich, meaty taste, texture and appearance. Partner (signed 2018/19) Program Goals 2019 Progress to Date Present Dairy Alternatives Milk, Yogurt, Cheese, Ice Cream ● CASE STUDY 3 motif Growing collaboration with emerging foodtech platform Motif building leading food science capabilities Smoother and creamier with consistent stretch and melt. FOODWORKS Leveraged Ginkgo's platform for growing set of ingredients from Day 1 Plant-Based Innovation New Forms and Functions, Improved Existing Foods Enhanced nutrition, texture and appearance. And unique forms that inspire new categories. Collaboration in Brief Motif FoodWorks, a plant-based food startup developing key ingredients for plant-based meats, dairy, and eggs (company was formed as a spin-out with strategic + financial capital) Engineer organisms to produce key plant-based proteins at industrial scale, enabling cost-effective new product innovations in food Completed programs are enabling product launches and supported a large Series B financing at a substantial step-up H1 UPDATE | AUGUST 2021 GINKGO BIOWORKS 21#22Motif contributes both Foundry Revenue and downstream value in the form of equity, which has seen substantial appreciation Foundry Revenue ($M) $25 $20 $15 $10 $5 $0 Foundry $19M 2019 $21M 2020 Foundry revenue generated across a number of discrete programs AgFUNDER Motif Ingredients Raises $90m Series A to Engineer Alternative Proteins in Ginkgo Bioworks Spin-Out February 26, 2019 Louisa Burwood-Taylor Downstream Value CBINSIGHTS OTPP-Backed Motif FoodWorks Raises $226M To Transform The Food Technology Market June 18, 2021 f y in When accepting equity in lieu of royalties, Ginkgo typically takes 30%+ stakes in newly formed companies (Platform Ventures) Fonterra CASE STUDY 3 motif Breakthrough LDC. Energy Louis Dreyfus Company Dairy for life FOODWORKS Global Investors LP BlackRock. ONTARIO TEACHERS' PENSION PLAN H1 UPDATE | AUGUST 2021 GINKGO BIOWORKS 22#23AGENDA H1 Revenue Update & Full Year Outlook Investor Presentation Supplement The Market for Cell Programming Downstream Value and Program Updates Biosecurity Q&A H1 UPDATE | AUGUST 2021 GINKGO BIOWORKS 23#24NATIONAL STRATEGY FOR THE COVID-19 RESPONSE AND PANDEMIC JANUARY 2021 Testing every school in America. Every student. Every week. Biden Administration to Invest More Than $12 Billion to Expand COVID-19 Testing PREPAREDNESS As part of President Biden's National Strategy for the COVID-19 Response and Pandemic Preparedness - PDF, the U.S. Department of Health and Human Services (HHS) will invest $10 billion from the American Rescue Plan to ramp up screening testing to help schools reopen, $2.25 billion to scale up testing in underserved populations, and provide new guidance on asymptomatic screening testing in schools, workplaces, and congregate settings. These measures are part of President Biden's strategy to increase COVID-19 testing nationwide as vaccinations increas FIND OUT HOW $10 Billion in Funding for School Screenings to Help Reopening $2.25 Billion in Screenings to Address Disparities and Advance Equity New CDC Guidance to Provide Clarity on Screening Testing Approaches Testing Ramp-Up Is Part of Biden's Overall Effort to Increase Testing Nationwide as Vaccinations Increase "COVID-19 testing is critical to saving lives and restoring economic activity," said HHS Acting Secretary Norris Cochran. "As part of the Biden Administration's National Strategy, HHS will continue to expand ur capacity to get testing to the individuals and the places that need it most, so we can prevent smission of the virus and defeat the pandemic." $400M+K12 statewide testing from contracts signed or in final stages of contracting (1) (1) Biosecurity contract value and performance is subject to Ginkgo's ability to conduct sufficient outreach to school districts, school adoption rates of Concentric and the volume of testing performed within contracted states. These state contracts can be paused or terminated early and there is significant uncertainty in the K-12 testing market in general as the facts and circumstances of the pandemic change regularly. (2) Contract value not specified, but state was allocated over $300 million in funding from the American Rescue Plan, for K-12 school testing Publicly Announced Major Contracts (contracts represent potential value over 2021-2022 school year) CALIFORNIA REPUBLIC N★C MAINE m Arizona Total Contract Value: up to $114M 250+ schools signed up to date California Total Contract Value: [not disclosed] 400+ schools signed up to date Maryland Total Contract Value: [not disclosed] 125+ schools signed up to date Maine Total Contract Value: [not disclosed] 250+ schools signed up to date New Hampshire Total Contract Value: [not disclosed] 20+ schools signed up to date North Carolina Total Contract Value: N/A(2) 50+ schools signed up to date Pennsylvania Total Contract Value: up to $87M Newly signed! (+additional states in contracting or not yet publicly disclosed) H 1 UPDATE | AUGUST 2021 GINKGO BIOWORKS 24#25School testing is an emergent need, but we believe biosecurity will be a permanent fixture in our lives Function Basis of Competition Broad Endpoint Coverage Surveillance: monitoring, looking for new threats Scale Number of noses, hospitals, farms, fields, labs, and sewage systems Robust Threat Identification Technology and Protocols Develop the best tests: leverage data to recognize threats before they occur Codebase Ability to identify emerging threats and design the most effective tests Rapid Response & Recovery Therapeutics Vaccines Early Warning Systems Prevent virus attacks, minimize effects, recover Foundry + Codebase Ability to rapidly develop and scale biological response H1 UPDATE | AUGUST 2021 GINKGO BIOWORKS 25#26Ginkgo has a responsibility to be at the forefront of the emerging biosecurity industry E Menu Q Search The DNA Cops Who Make Sure the World's Deadliest Viruses Aren't Rebuilt Ginkgo Bioworks is helping stop a new class of lethal biological weapons from being created. By Rebecca Spalding June 27, 2018, 2:30 PM GMT+5:30 Bloomberg "We are doing more of this genetic engineering than anybody, we think we're going to get better at it than anybody, so we have a responsibility to be keeping our eye on both sides of that coin," Kelly said. "How do we protect and defend against that while protecting our ability to get all the positive outputs of biotechnology?" Sign In Subscribe H1 UPDATE | AUGUST 2021 GINKGO BIOWORKS 26#27We believe... 1 Cell programming is starting to become mainstream. We have increased our 2021 outlook for number of new programs from 23 to 30 due to higher-than-expected inbound interest from potential customers and enhanced credibility from completing programs. 2 Downstream value will become more valuable than Foundry service revenue. Foundry service revenue de-risks platform investments, but "wins" come from successful programs. We've heard a lot of questions about how downstream value works so we're giving 3 near-term case studies. 3 Delta sucks. And so will the next thing. Biosecurity will be a new market separate from diagnostics and we are becoming a leader due to our initial K-12 testing offering. We are now expecting our revenue to be at least $75 million for the full year. H1 UPDATE | AUGUST 2021 GINKGO BIOWORKS 27#28AGENDA H1 Revenue Update & Full Year Outlook Investor Presentation Supplement Q&A H1 UPDATE | AUGUST 2021 GINKGO BIOWORKS 28#29Designed by Ginkgo Born in Boston 000000 0000 000000 000000 APPENDIX 29#30Ginkgo to Become Fully Public Company August 11: SEC Declares S-4 Effective & PIPE S-1 Filed September 14: Soaring Eagle Extraordinary General Meeting and Shareholder Vote September 16: Expected Closing Date We look forward to seeing you at NYSE:DNA soon H 1 UPDATE | AUGUST 2021 GINKGO BIOWORKS 30

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