#1AMD FIRST QUARTER 2022 FINANCIAL RESULTS MAY 3, 2022#22 CAUTIONARY STATEMENT This presentation contains forward-looking statements concerning Advanced Micro Devices, Inc. (AMD) such as the features, functionality, performance, availability, timing and expected benefits of AMD products; that AMD's acquisition of Xilinx, Inc. will be non-GAAP EPS and free cash flow accretive in the first year; AMD's expected product and revenue synergies from the acquisition of Xilinx, Inc.; and AMD's expected second quarter 2022 and fiscal 2022 financial outlook, including revenue non-GAAP gross margin, non-GAAP operating expenses, non-GAAP operating expenses as a percentage of revenue, non-GAAP interest expense, taxes and other, non-GAAP tax rates and diluted share count, which are made pursuant to the Safe Harbor provisions of the Private Securities Litigation Reform Act of 1995. Forward-looking statements are commonly identified by words such as "would," "may," "expects," "believes," "plans," "intends," "projects" and other terms with similar meaning. Investors are cautioned that the forward-looking statements in this presentation are based on current beliefs, assumptions and expectations, speak only as of the date of this presentation and involve risks and uncertainties that could cause actual results to differ materially from current expectations. Such statements are subject to certain known and unknown risks and uncertainties, many of which are difficult to predict and generally beyond AMD's control, that could cause actual results and other future events to differ materially from those expressed in, or implied or projected by, the forward-looking information and statements. Material factors that could cause actual results to differ materially from current expectations include, without limitation, the following: Intel Corporation's dominance of the microprocessor market and its aggressive business practices; global economic uncertainty; loss of a significant customer; impact of the COVID-19 pandemic on AMD's business, financial condition and results of operations; competitive markets in which AMD's products are sold; market conditions of the industries in which AMD products are sold; cyclical nature of the semiconductor industry; quarterly and seasonal sales patterns; AMD's ability to adequately protect its technology or other intellectual property; unfavorable currency exchange rate fluctuations; ability of third party manufacturers to manufacture AMD's products on a timely basis in sufficient quantities and using competitive technologies; availability of essential equipment, materials, substrates or manufacturing processes; ability to achieve expected manufacturing yields for AMD's products; AMD's ability to introduce products on a timely basis with expected features and performance levels; AMD's ability to generate revenue from its semi-custom SoC products; potential security vulnerabilities; potential security incidents including IT outages, data loss, data breaches and cyber-attacks; uncertainties involving the ordering and shipment of AMD's products; AMD's reliance on third-party intellectual property to design and introduce new products in a timely manner; AMD's reliance on third-party companies for design, manufacture and supply of motherboards, software and other computer platform components; AMD's reliance on Microsoft and other software vendors' support to design and develop software to run on AMD's products; AMD's reliance on third-party distributors and add-in-board partners; impact of modification or interruption of AMD's internal business processes and information systems; compatibility of AMD's products with some or all industry-standard software and hardware; costs related to defective products; efficiency of AMD's supply chain; AMD's ability to rely on third party supply-chain logistics functions; AMD's ability to effectively control sales of its products on the gray market; impact of government actions and regulations such as export administration regulations, tariffs and trade protection measures; AMD's ability to realize its deferred tax assets; potential tax liabilities; current and future claims and litigation; impact of environmental laws, conflict minerals-related provisions and other laws or regulations; impact of acquisitions, joint ventures and/or investments on AMD's business and AMD's ability to integrate acquired businesses, such as Xilinx; impact of any impairment of the combined company's assets on the combined company's financial position and results of operation; restrictions imposed by agreements governing AMD's notes, the guarantees of Xilinx's notes and the revolving credit facility; AMD's indebtedness; AMD's ability to generate sufficient cash to meet its working capital requirements or generate sufficient revenue and operating cash flow to make all of its planned R&D or strategic investments; political, legal, economic risks and natural disasters; future impairments of goodwill and technology license purchases; AMD's ability to attract and retain qualified personnel; AMD's stock price volatility; and worldwide political conditions. Investors are urged to review in detail the risks and uncertainties in AMD's Securities and Exchange Commission filings, including but not limited to AMD's most recent reports on Forms 10-K and 10-Q. NON-GAAP FINANCIAL MEASURES In this presentation, in addition to GAAP financial results, AMD has provided non-GAAP financial measures including non-GAAP gross profit, non-GAAP operating expenses, non-GAAP operating income, non-GAAP net income, non-GAAP earnings per share and free cash flow. AMD uses a normalized tax rate in its computation of the non-GAAP income tax provision to provide better consistency across the reporting periods. For full year 2022, AMD uses a projected non-GAAP tax rate of 13%, which excludes the tax impact of pre-tax non-GAAP adjustments, reflecting currently available information, and a projected non-GAAP cash tax rate of approximately 10% that includes the projected current income tax liability plus known foreign with holding tax obligations paid expressed as a percentage of non-GAAP profit before tax. In addition, AMD provided non- GAAP financial measures excluding Xilinx, including revenue, gross profit and operating income, and Xilinx pro forma revenue for the three months ended March 26, 2022 as supplemental information. AMD is providing these financial measures because it believes this non-GAAP presentation makes it easier for investors to compare its operating results for current and historical periods and also because AMD believes it assists investors in comparing AMD's performance across reporting periods on a consistent basis by excluding items that it does not believe are indicative of its core operating performance. The non-GAAP financial measures disclosed in this presentation should be viewed in addition to and not as a substitute for or superior to AMD's reported results prepared in accordance with GAAP and should be read only in conjunction with AMD's Consolidated Financial Statements prepared in accordance with GAAP. These non-GAAP financial measures referenced are reconciled to their most directly comparable GAAP financial measures in the Appendices at the end of this presentation. This presentation also contains forward-looking non-GAAP measures concerning AMD's financial outlook such as gross margin, operating expenses, interest expense, taxes and other. These forward- looking non-GAAP measures are based on current expectations as of May 3, 2022, and assumptions and beliefs that involve numerous risks and uncertainties. AMD undertakes no intent or obligation to publicly update or revise its forward-looking statements made in this presentation except as may be required by law. Q1 2022 FINANCIAL RESULTS | MAY 3, 2022 AMD#33 Best Product Portfolio in History Q1 2022 FINANCIAL RESULTS | MAY 3, 2022 AMD OUR JOURNEY Expanding Customer & Partner Ecosystem Significant Business Acceleration Outstanding Financial Performance AMD#44 $ Xilinx Acquisition Creates Industry's High-Performance and Adaptive Computing Leader Industry-Leading Products Q1 2022 FINANCIAL RESULTS | MAY 3, 2022 AMD Diversified and Growing Markets Data Center Momentum Non-GAAP Margin Expansion Non-GAAP EPS and Free Cash Flow Accretive for 2022 AMD#55 ZEN 3 XILINX OUR LEADERSHIP TECHNOLOGY AMD AMD RDNA 2 CDNA 2 ZYNQ INDUSTRY LEADING IP Executing leadership CPU, GPU, FPGA and Adaptive SoC products and roadmaps. Q1 2022 FINANCIAL RESULTS | MAY 3, 2022 S ar KA THE 5-7 ADVANCED TECHNOLOGY Driving leadership process technology and 3D chiplet packaging gefeder DATA CENTER LEADERSHIP Driving innovation in cloud, enterprise, Al and accelerated computing AMD XILINX ROCM VITIS. SOFTWARE ENABLEMENT Open-source software co-designed with hardware, and optimized for performance across heterogenous solutions AMD#66 OUR BEST EVER PRODUCT PORTFOLIO INSTING EPYC FRE ADVER DATA CENTER XILINX VIRTEX UraSCALE Leadership AMD EPYC server processors for cloud, enterprise and HPC. Data center solutions with high-performance AMD Instinct accelerators, SmartNICs and adaptive SOC accelerators Q1 2022 FINANCIAL RESULTS | MAY 3, 2022 www. AMD RYZEN 6000 SERIES |||||||||||||| CLIENT AMD BREE Leadership processors for ultrathin, commercial and gaming notebooks and consumer, gaming and workstation desktop PCs GAMING Top-to-bottom graphics cards and game consoles based on RDNA 2 Architecture XILINXⓇ ΖΥΝΟ.. ZEN 25 XILINX VIRTEX Ultra SCALE AMD EPYC SHREDDED EMBEDDED EXILINX 8888888888 TO CPUS, FPGAs and Adaptive SoCs for a broad set of markets See endnotes R5K-002 and CZM-35 AMD#7QUARTERLY SUMMARY Q1 2022 Record revenue of $5.9 billion grew 71% y/y and 22% q/q ▪ Gross margin 48%, up 2 pp y/y and down 2 pp q/q Non-GAAP gross margin 53%, up 7 pp y/y and 3pp q/q ■ Operating income $951 million or 16% of revenue ▪ Record Non-GAAP operating income $1.8 billion or 31% of revenue ▪ Net income $786 million; Record Non-GAAP net income $1.6 billion Diluted EPS $0.56; Record Non-GAAP diluted EPS $1.13 ▪ Record operating cash $995 million; record free cash flow $924 million Cash, cash equivalents and short-term investments $6.5 billion AMD financial results, excluding Xilinx: Revenue of $5.3 billion up 55% y/y and 10% q/q Non-GAAP gross margin 51%, up 5 pp y/y and 1 pp q/q - Non-GAAP operating income $1.6 billion or 30% of revenue Repurchased $1.9 billion of stock; $8.3 billion in remaining authorization 7 Q1 2022 FINANCIAL RESULTS | MAY 3, 2022 1. Quarterly Revenue ($B) $3.4 1 Q1 2021 +71% y/y $5.9 Q1 2022 See Appendices for GAAP to Non-GAAP reconciliation. AMD#8■ 8 COMPUTING AND GRAPHICS SEGMENT Q1 2022 Record Revenue $2.8 billion • Up 33% y/y driven by RyzenTM and RadeonTM processor sales Up 8% q/q driven by Ryzen processor sales ● Average Selling Prices (ASP) Client processor ASP grew y/y and q/q driven by a richer mix of Ryzen processor sales • GPU ASP up y/y driven by high-end Radeon processor sales; down q/q due to lower mix of data center GPUs Record Operating Income $723 million or 26% of revenue ● Strategic Announced Ryzen 7 5800X3D desktop CPU with AMD 3D V-Cache technology featuring 3D stacked chiplets • Launched Ryzen 6000 mobile processors and Ryzen 6000 PRO processors for the commercial market ● Ryzen ThreadripperTM PRO WX-Series processors power Lenovo ThinkStation P620 workstations ● ● ● · Desktop GPU sales driven by Radeon 6000 series graphics cards; launched Radeon 6000 mobile GPUs • Launched ROCm 5 software suite targeting Exascale-class HPC and Al applications ● Q1 2022 FINANCIAL RESULTS | MAY 3, 2022 AMD#9■ 9 Record Revenue $2.5 billion Up 88% y/y and 13% q/q driven by record EPYCTM processor, semi-custom and embedded revenue ● ENTERPRISE, EMBEDDED AND SEMI-CUSTOM SEGMENT Q1 2022 ▪ Record Operating Income $881 million or 35% of revenue Improvements primarily driven by higher revenue and an $83 million licensing gain Strategic news and highlights • Announced plans to acquire Pensando for approximately $1.9 billion to drive data center solution capabilities Hyperscalers continue to expand internal infrastructure with AMD EPYC processors; 70 new AMD-powered cloud instances also launched from Alibaba, Amazon, Microsoft Azure, Google and others Strong growth in Enterprise server revenue with solid pipeline. • Announced availability of 3rd Gen AMD EPYC processors with AMD 3D V-Cache Technology ● • Semi-custom sales driven by strong demand for Sony and Microsoft game consoles and Valve's Steam Deck ● Q1 2022 FINANCIAL RESULTS | MAY 3, 2022 AMD#1010 AMD's acquisition of Xilinx closed on February 14, 2022 ▪ Xilinx adds multiple high-margin, long-term revenue streams spanning a new set of markets for AMD ▪ Xilinx generated $559 million of revenue for the six weeks of Q1'22 after the transaction closed Operating income of $233 million for the six weeks of Q1'22 after the transaction closed ▪ On a pro-forma basis for the full quarter, Xilinx generated $1.04 billion of revenue, up 22% y/y Strategic news and highlights Strong demand across all the Xilinx end markets ■ ● ● ● XILINX Q1 2022 Expanded Versal product lineup with the first customer shipments of Versal HBM adaptive SOCS Expanded FPGA-as-a-Service and SmartNIC deployments at Tier-1 hyperscalers Record revenue from auto, industrial, vision and healthcare, and consumer customers Q1 2022 FINANCIAL RESULTS | MAY 3, 2022 AMD#1111 7000 6000 5000 4000 3000 2000 $1,932 Q2'20 $2,801 Q3'20 Q1 2022 FINANCIAL RESULTS | MAY 3, 2022 REVENUE TREND ($ IN MILLIONS) $3,244 Q4'20 $3,445 Q1'21 $3,850 Q2'21 $4,313 Q3'21 SIGNIFICANT REVENUE GROWTH $4,826 Q4'21 +71% y/y $5,887 Q1'22 AMD#1212 44% Q2'20 44% Q3'20 Q1 2022 FINANCIAL RESULTS | MAY 3, 2022 GROSS MARGIN TREND (GAAP AND NON-GAAP)¹ 45% 46% 48% Q1'21 Q4'20 GROSS MARGIN EXPANSION Q2'21 48% Q3'21 50% Q4'21 GAAP +2 pp y/y Non-GAAP + 7pp y/y 53% (Non-GAAP) 48% Q1'22 1. See Appendices for GAAP to Non-GAAP reconciliation. GAAP and non-GAAP gross margin are the same for all quarters except for Q1'22. AMD#13Axis Title 13 $0.13 Q2'20 EARNINGS PER SHARE TREND (GAAP) $0.32 Q3'20 Q1 2022 FINANCIAL RESULTS | MAY 3, 2022 $1.45 $1.06 Valuation Allowance Release $0.39 Q4'20 $0.45 Q1'21 $0.58 Q2'21 $0.75 Q3'21 Y/Y GROWTH IN PROFITABILITY $0.80 Q4'21 +24% y/y $0.56 Q1'22 1. In Q4 2020, AMD released $1.3 billion of its $2.9 billion income tax valuation allowance. The valuation allowance release had a $1.06 benefit to Q4 2020 earnings per share. AMD#1414 $0.18 Q2'20 EARNINGS PER SHARE TREND (NON-GAAP)¹ $0.41 Q3'20 Q1 2022 FINANCIAL RESULTS | MAY 3, 2022 $0.52 $0.52 $0.63 Q2'21 $0.73 Q4'20 Q1'21 STRONG EPS TRAJECTORY Q3'21 $0.92 Q4'21 +117% y/y $1.13 Q1'22 1. See Appendices for GAAP to Non-GAAP reconciliation AMD#1515 Q1 2022 SUMMARY P&L - GAAP ($ in millions, except per share data) Revenue Gross Profit Gross Margin % Operating Expenses Operating Expense/Revenue % Operating Income Operating Margin % Net Income ¹ Earnings Per Share ¹,2 Q1 2022 FINANCIAL RESULTS | MAY 3, 2022 Q1'22 $5,887 $2,818 48% $1,950 33% $951 16% $786 $0.56 Q1'21 $3,445 $1,587 46% $929 27% $662 19% $555 $0.45 Y/Y Up 71% Up 78% Up 190 bps Up 110% Up 6pp Up 44% Down 3pp Up 42% Up 24% Q4'21 $4,826 $2,426 50% $1,223 25% $1,207 25% $974 $0.80 Q/Q Up 22% Up 16% Down 240 bps Up 59% Up 8pp Down 21% Down 9pp Down 19% Down 30% 1. Includes a higher tax rate beginning in Q1 2021 2. See Appendices for share count reference. AMD#1616 Q1 2022 SUMMARY P&L - NON-GAAP¹ ($ in millions, except per share data) Revenue Gross Profit Gross Margin % Operating Expenses Operating Expense/Revenue % Operating Income Operating Margin % Net Income Earnings Per Share¹ Q1 2022 FINANCIAL RESULTS | MAY 3, 2022 Q1'22 $5,887 $3,100 53% $1,346 23% $1,837 31% $1,589 $1.13 Q1'21 $3,445 $1,588 46% $830 24% $762 22% $642 $0.52 Y/Y Up 71% Up 95% Up 660 bps Up 62% Down 1pp Up 141% Up 9pp Up 148% Up 117% Q4'21 $4,826 $2,427 50% $1,103 23% $1,328 27% $1,122 $0.92 Q/Q Up 22% Up 28% Up 240 bps Up 22% Flat Up 38% Up 4pp Up 42% Up 23% 1. See Appendices for GAAP to Non-GAAP reconciliation and share count reference AMD#1717 Q1 2022 - AMD RESULTS EXCLUDING XILINX¹ ($ in millions, Non-GAAP measures) Revenue Gross Profit Gross Margin % Operating Income Operating Margin % Q1 2022 FINANCIAL RESULTS | MAY 3, 2022 Q1'22 $5,328 $2,712 51% $1,604 30% Q1'21 $3,445 $1,588 46% $762 22% Y/Y Up 55% Up 71% Up 480 bps Up 110% Up 8pp Q4'21 $4,826 $2,427 50% $1,328 27% Q/Q Up 10% Up 12% Up 60 bps Up 21% Up 3pp 1. See Appendices for GAAP to Non-GAAP reconciliation AMD#1818 ($ in millions) Computing and Graphics Net Revenue Operating Income Enterprise, Embedded and Semi-Custom Net Revenue Operating Income Xilinx¹ Net Revenue Operating Income All Other Category Operating Loss TOTAL Net Revenue Operating Income Q1 2022 SEGMENT RESULTS Q1 2022 FINANCIAL RESULTS | MAY 3, 2022 Q1'22 $2,802 $723 $2,526 $881 $559 $233 $(886) $5,887 $951 Q1'21 $2,100 $485 $1,345 $277 $(100) $3,445 $662 Y/Y Up 33% Up 49% Up $88% Up 218% | Up 786% Up 71% Up 44% Q4'21 $2,584 $566 $2,242 $762 | $(121) $4,826 $1,207 Q/Q Up 8% Up 28% Up 13% Up 16% | | Up 632% Up 22% Down 21% 1. Xilinx represents partial quarter revenue following the close of the acquisition on February 14, 2022. AMD#1919 Q1 2022 SUMMARY BALANCE SHEET ITEMS ($ in millions) Cash, Cash Equivalents and Short-term Investments Accounts Receivable, Net Inventories Total Debt (principal amount)1 Total Debt, Net¹ Q1 2022 FINANCIAL RESULTS | MAY 3, 2022 Q1'22² $6,532 $3,677 $2,431 $1,813 $1,787 Q1'21 $3,116 Up $3,416 $2,178 $1,653 $314 Y/Y $313 Up $1,499 Up $778 Up $1,499 Up $1,474 STRONG BALANCE SHEET 1. 2. Q4'21 $3,608 $2,706 $1,955 $313 $313 Q/Q Up $2,924 Up $971 Up $476 Up $1,500 Up $1,474 See Appendices for Total Debt reconciliation. Includes contributions from Xilinx. AMD#2020 1. 2. Revenue FINANCIAL OUTLOOK - NON-GAAP Gross Margin % Operating Expenses Operating Expenses/Revenue % Interest Expense, Taxes and Other Effective Tax Rate Cash Tax Rate Diluted Share Count² Q2 2022 ~$6.5 Billion +/- $200 Million ~54% Q1 2022 FINANCIAL RESULTS | MAY 3, 2022 -$1.56 Billion ~24% ~$270 Million ~1.64 billion shares 1 FY 2022 -$26.3 Billion Growth of ~60% y/y ~54% ~13% of pre-tax income ~10% of pre-tax income ~24% ~1.58 billion shares See Cautionary Statement on Slide 2. These forward-looking outlook statements and non-GAAP measures are based on current expectations as of May 3, 2022, and assumptions and beliefs that involve numerous risks and uncertainties. AMD undertakes no intent or obligation to publicly update or revise its outlook statements as a result of new information, future events or otherwise, except as may be required by law. All items, except revenue, are on a non-GAAP basis. Adjustments to arrive at the GAAP financial outlook typically include stock-based compensation, amortization of acquired intangible assets, income tax provision, equity income in investee, and other non- recurring items such as loss on debt redemption/conversion, impairment charges and acquisition-related costs. The timing and impact of such adjustments are dependent on future events that are typically uncertain or outside of AMD's control; therefore, a reconciliation to equivalent GAAP measures is not practicable at this time. Refer to Diluted Share Count overview in the Appendices AMD#2121 Q1 2022 SUMMARY Record revenue $5.9B Up 71% Y/Y, 22% Q/Q Q1 2022 FINANCIAL RESULTS | MAY 3, 2022 Gross Margin of 48% Non-GAAP GM of 53% Record Non-GAAP Profitability COMPLETED ACQUISITION OF XILINX Repurchased $1.9B Common Stock AMDL#2222 CDP SUPPLIER ENGAGEMENT LEADER 2021 AMD'S COMMITMENT TO ESG SILVER 2022 ecovadis Sustainability Rating RBA COMPASS AWARD 2020 INNOVATION ENVIRONMENTAL Steadfast commitment to environmental stewardship and contributing to our local communities Q1 2022 FINANCIAL RESULTS | MAY 3, 2022 Bloomberg Gender-Equality Index 2022 E BEST HUMAN RIGHTS PLACES TO WORK 2022 for LGBTQ+ Equality 100% CORPORATE EQUALITY INDEX SOCIAL Creating a culture that drives innovation by fostering diversity, inclusion and belonging 3BL DIA ME 100 BEST CORPORATE CITIZENS 2021 FTSE4Good Corporate ESG Performance RATED BY ISS ESG GOVERNANCE CORPORATE RESPONSIBILITY REPORT ON AMD.COM Prime Delivering industry leading products with integrity, innovation and quality in order to help solve global challenges AMD#2323 AMD BUILDING THE BEST Leadership Roadmaps Q1 2022 FINANCIAL RESULTS | MAY 3, 2022 Increasing Market Share Execution Excellence Outstanding Financial Performance AMD#2424 APPENDICES Reconciliation of GAAP to Non-GAAP Gross Profit and Gross Margin (Millions) (Unaudited) GAAP gross profit GAAP gross margin % Stock-based compensation Acquisition-related costs (1) Amortization of acquired intangible assets Non-GAAP gross profit Non-GAAP gross margin % Reconciliation of GAAP to Non-GAAP Operating Expenses Q4'21 Q1'21 1,950 $ 929 $ 1,223 33% 27% 25% 170 84 111 141 15 9 293 1,346 $ 23% (Millions) (Unaudited) GAAP operating expenses GAAP Operating Expenses/Revenue % Stock-based compensation Acquisition-related costs (1) Q1'21 Q2'21 Q3'21 Q4'21 Q1'22 Q2'20 Q3'20 Q4'20 $ 848 $ 1,230 $ 1,451 $ 1,587 $ 1,830 $2,086 $ 2,426 $ 2,818 44% 44% 45% 46% 48% 50% 48% 48% 2 2 1 1 1 1 4 92 186 $ 850 $ 1,231 $ 1,452 $ 1,588 $ 1,832 $2,087 $ 2,427 $ 3,100 44% 44% 45% 46% 48% 48% 53% 50% Amortization of acquired intangible assets Non-GAAP operating expenses Non-GAAP Operating Expenses/Revenue % $ $ Q1'22 830 $ 24% 1,103 23% 1 I (1) Acquisition-related costs primarily comprised of transaction costs, purchase price adjustments for inventory and certain compensation charges. Q1 2022 FINANCIAL RESULTS | MAY 3, 2022 AMD#25APPENDICES Reconciliation of GAAP Operating Income to Non-GAAP Operating Income (Millions) (Unaudited) GAAP operating income GAAP operating margin % Stock-based compensation Acquisition-related costs (1) Amortization of acquired intangible assets Non-GAAP operating income Non-GAAP operating margin % 25 Q1 2022 FINANCIAL RESULTS | MAY 3, 2022 Q1'22 $ $ 951 Q1'21 Q4'21 $ 662 $ 1,207 19% 25% 85 112 15 9 16% 174 233 479 1,837 $ 762 $ 31% 22% — 1,328 27% (1) Acquisition-related costs primarily comprised of transaction costs, purchase price adjustments for inventory and certain compensation charges. AMD#26APPENDICES Reconciliation of GAAP to Non-GAAP Net Income / Earnings Per Share (Millions, except per share data) (Unaudited) GAAP net income / earnings per share Loss on debt redemption/conversion (Gains) losses on equity investments, net Non-cash interest expense related to convertible debt Stock-based compensation Equity income in investee Acquisition-related costs (1) Amortization of acquired intangible assets Release of valuation allowance on deferred tax assets Income tax provision Non-GAAP net income / earnings per share Shares used and net income adjustment in earnings per share calculation 26 Q2'20 Q3'20 Q1'21 Q2'21 $ 157 $0.13 $390 $ 0.32 $1,781 $1.45 $ 555 $ 0.45 $710 $ 0.58 $923 $0.75 38 0.03 16 0.01 14 0.02 1 I I - 2 60 (1) I I I I I I 0.05 T I I T - - 1,227 $ 3 1,227 $ 1 2 76 (1) I - I - I 0.06 I I Q4'20 — 1,215 $1 1,230 $1 I 79 (3) 14 T 0.06 I 0.01 (1,301) (1.06) (2) (4) 50 0.05 (25)| (0.03) $ 216 $0.18 $ 501 $0.41 $636 $0.52 $ 642 $ 0.52 I 1,226 $ - 1,232 $ T — I 85 0.07 (2) 15 0.01 I I 1,231 $ - 1,233 $ I - I 83 0.06 (2) 10 0.01 I I T Q3'21 1,232 $ - 1,232 $ (60)| (0.05) I 99 0.08 (2) I 8 0.01 - T - I Q4'21 Q1'22 $974 $0.80 $786 $ 0.56 1,230 $ 1,230 $ - (4) - I 9 112 0.09 — I I I 31 I I - I I Shares used in per share calculation (GAAP) (2) Interest expense add back to GAAP net income (2) Shares used in per share calculation (Non-GAAP) Interest expense add back to Non-GAAP net income (1) Acquisition-related costs primarily comprised of transaction costs, purchase price adjustments for inventory and certain compensation charges. (2) Q2'20 GAAP diluted EPS calculation includes 31 million shares related to the assumed conversion of the Company's 2026 Convertible Notes and the associated $3 million interest expense add-back to net income under the "if converted" method. Q3'20 and Q4'20 GAAP diluted EPS calculation includes 11 million and 3 million shares, respectively, related to the assumed conversion of the Company's 2026 Convertible Notes and the associated $1 million and $0 million interest expense, respectively, add-back to net income under the "if converted" method. The 20 million (15 million weighted-average), 8 million shares (6 million weighted-average) and 3 million shares (2 million weighted-average) issued in exchange for $165 million, $60 million and $24 million of convertible debt in Q3'20, Q4'20 and Q1'21, respectively, were not included as their inclusion would have been anti-dilutive. Q1 2022 FINANCIAL RESULTS | MAY 3, 2022 AMD 44 1,222 $ - 1,222 $ (75) (0.06) 0.03 (124) (0.09) (24)| (0.02) $ 778 $0.63 $ 893 $0.73 $ 1,122 $ 0.92 $1,589 $ 1.13 0.03 174 0.12 (3) 233 479 - 0.17 0.34 1,410 $ 1,410 $#27APPENDICES Reconciliation of Operating Cash Flow to Free Cash Flow Q1'22 995 17% (71) 924 16% 27 (Millions) (Unaudited) Operating cash flow Operating cash flow margin % Purchases of property and equipment Free cash flow Free cash flow margin % Total Debt (Net) (Millions) (Unaudited) 2.95% Senior Notes due 2024 2.375% Senior Notes due 2030 7.50% Senior Notes due 2022 2.125% Convertible Senior Notes due 2026 Total Debt (principal amount) Unamortized debt discount and issuance costs Total Debt (net) Q1 2022 FINANCIAL RESULTS | MAY 3, 2022 $ $ Q1'22 750 $ 750 312 1 1,813 (26) 1,787 $ $ Q1'21 I T 312 2 314 (1) 313 $ $ Q4'21 I 312 1 313 T $ 313 AMD#28APPENDICES Reconciliation of AMD GAAP to AMD Non-GAAP Excluding Xilinx (Millions) (Unaudited) AMD GAAP Stock-based compensation Acquisition-related costs (1) Amortization of acquired intangible assets AMD Non-GAAP Xilinx segment AMD Non-GAAP Excluding Xilinx Revenue 28 Q1 2022 FINANCIAL RESULTS | MAY 3, 2022 $ 5,887 5,887 559 $ 5,328 Gross Profit $ 2,818 4 92 186 3,100 388 $ 2,712 Q1'22 Gross Margin % 48% 53% 51% Operating Income $ (1) Acquisition-related costs primarily comprised of transaction costs, purchase price adjustments for inventory and certain compensation charges. 951 174 233 479 1,837 233 1,604 Operating Margin % 16% 31% 30% AMD#29APPENDICES Reconciliation of Xilinx Segment Revenue to Xilinx Pro Forma Revenue (Millions) (Unaudited) Xilinx Segment (1) Xilinx Pre-Acquisition (2) Xilinx Pro Forma (3) Q1'22 Revenue 29 Q1 2022 FINANCIAL RESULTS | MAY 3, 2022 559 477 1,036 (1) Represents unaudited Xilinx revenue from the date of acquisition, February 14, 2022, through March 26, 2022. (2) Represents unaudited Xilinx revenue from January 2, 2022 to February 13, 2022. (3) The unaudited Xilinx pro form a revenue represents the three-month period beginning January 2, 2022 through March 26, 2022. The pro form a revenue is presented for informational purposes only. AMD#3030 APPENDICES Share Count Overview Shares (millions) (1) Basic Shares Dilutive impacts from: Employee Equity Grants (2) Xilinx Assumed Awards Diluted Shares Q4'21 Actual Q1 2022 FINANCIAL RESULTS | MAY 3, 2022 1,208 14 1,222 Q1'22 Q2'22 2022 Actual Estimate Estimate 1,393 1,622 1,568 13 4 1,410 13 6 1,641 12 4 1,584 The table above provides actual share count for Q4'21 and Q1'22 and an estimate of share count to use when calculating GAAP and non-GAAP diluted earnings per share for Q2'22 and FY 2022. (1) Share counts are weighted average shares. (2) The dilutive impact of employee equity grants is based on the Treasury Stock method and is dependent upon the average stock price during the period. The Q4'21 and Q1'22 average stock price was $131.29 and $121.81, respectively. The Q1'22 average stock price of $121.81 was assumed for Q2'22 and FY22 average stock price estimates. AMD#3131 ENDNOTES TM R5K-002: Testing by AMD Performance labs as of 5/28/2021 based on the average FPS of 20 PC games at 1920x1080 with the High image quality preset using an AMD Ryzen ™M 9 5900X processor vs. Core i9-11900K. For Ryzen 5000 G-Series processors testing as of 5/5/2021 based on the average FPS of 11 PC games at 1920x1080 with the low image quality preset using an AMD Ryzen 7 5700G vs Core i7-11700, both configured with integrated graphics. Results may vary. R5K-002.R5K-050: Testing by AMD Performance Labs as of December 11, 2020 using an AMD Ryzen 9 5900 and Intel Core i9-10900, each similarly configured and tested with an NVIDIA GeForce RTX 2080 Ti graphics card. Results may vary. R5K-002. CZM-35: Tested by AMD Labs in December 2020. The Ryzen 5000 series mobile processors are the fastest mobile processors with the highest-performing single-thread and multi-thread performance available on an x86 mobile processor, measured with Cinebench R.20 1T and Cinebench R20 nT respectively, using similarly configured systems with Ryzen 9 4900H, Ryzen 9 5980HX and Ryzen 5980HS processors vs i9-10980HK, Core i7-1185G7 processors. Performance may vary. CZM-35. DISCLAIMERS AND ATTRIBUTIONS The information contained herein is for informational purposes only and is subject to change without notice. Timelines, roadmaps, and/or product release dates shown in these slides are plans only and subject to change. While every precaution has been taken in the preparation of this document, it may contain technical inaccuracies, omissions and typographical errors, and AMD is under no obligation to update or otherwise correct this information. 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Other product names used in this presentation are for identification purposes only and may be trademarks of their respective companies. FIRST QUARTER 2022 FINANCIAL RESULTS | MAY 3, 2022 AMD