#1MERCK INVENTING FOR LIFE Merck Q2 2023 Earnings August 1, 2023#2Agenda Strategy and Business Update Rob Davis Chairman and Chief Executive Officer Business/Financial Results and Outlook Caroline Litchfield Chief Financial Officer Research Update Dr. Dean Li President, Merck Research Laboratories Question & Answer Session MERCK 2#3Forward-looking statement of Merck & Co., Inc., Rahway, N.J., USA This presentation of Merck & Co., Inc., Rahway, N.J., USA (the "company") includes "forward-looking statements" within the meaning of the safe harbor provisions of the U.S. Private Securities Litigation Reform Act of 1995. These statements are based upon the current beliefs and expectations of the company's management and are subject to significant risks and uncertainties. There can be no guarantees with respect to pipeline candidates that the candidates will receive the necessary regulatory approvals or that they will prove to be commercially successful. If underlying assumptions prove inaccurate or risks or uncertainties materialize, actual results may differ materially from those set forth in the forward-looking statements. Risks and uncertainties include but are not limited to, general industry conditions and competition; general economic factors, including interest rate and currency exchange rate fluctuations; the impact of the global outbreak of novel coronavirus disease (COVID-19); the impact of pharmaceutical industry regulation and health care legislation in the United States and internationally; global trends toward health care cost containment; technological advances, new products and patents attained by competitors; challenges inherent in new product development, including obtaining regulatory approval; the company's ability to accurately predict future market conditions; manufacturing difficulties or delays; financial instability of international economies and sovereign risk; dependence on the effectiveness of the company's patents and other protections for innovative products; and the exposure to litigation, including patent litigation, and/or regulatory actions. The company undertakes no obligation to publicly update any forward-looking statement, whether as a result of new information, future events or otherwise. Additional factors that could cause results to differ materially from those described in the forward-looking statements can be found in the company's Annual Report on Form 10-K for the year ended December 31, 2022 and the company's other filings with the Securities and Exchange Commission (SEC) available at the SEC's Internet site (www.sec.gov). MERCK 3#4MERCK INVENTING FOR LIFE Strategy & Business Update Rob Davis Chairman and Chief Executive Officer#5Delivered on our key strategic priorities in Q2 2023 < Advanced the pipeline to meet patient unmet need Executed on strategic business development to enhance pipeline Achieved strong commercial and financial performance Created long-term value for patients and shareholders 00000 MERCK 5#6Strong underlying Q2 performance1 Q2 Worldwide Sales Full Year Sales $59.3B +22% GUIDANCE RANGE $58.6B-$59.6B $15.0B +3% +14% ex-Exchange, ex-LAGEVRIO² Q2 Non-GAAP LPS3 $48.7B +17% 2021 Full Year Non-GAAP EPS5 2022 2023 ($2.06) N/M² Includes one-time charge of $4.02 from Prometheus acquisition $5.37 2021 $7.48 2022 GUIDANCE RANGE $2.95 - $3.05 1. Results from continuing operations attributable to Merck & Co., Inc. 2. Excludes Lagevrio sales of $203 million in 2Q23 and $1.2 billion in 2022. 3. GAAP LPS (Loss Per Share) of ($2.35). Both 2Q23 GAAP and non-GAAP LPS reflect a charge of $10.2 billion or $4.02 per share for the acquisition of Prometheus Biosciences, Inc. 4. Not meaningful 5. Merck does not exclude expenses for upfront and milestone payments related to collaborations and licensing agreements, or charges related to pre-approval assets obtained in transactions accounted for as asset acquisitions from its non-GAAP results. YTD 2023 non-GAAP results include an aggregate $11.6 billion or $4.53 per share of R&D expenses related to the Prometheus and Imago acquisitions and upfront payment for the license and collaboration agreement with Kelun. Full year 2022 non-GAAP results include $690 million or $0.22 of such charges. Full year 2021 non-GAAP results include $1.7 billion or $0.65 of such charges. For 2023, outlook does not assume any additional significant potential business development transactions. 2023 MERCK 6#7Advancing and augmenting our deep pipeline Q Oncology Highlighted important data at ASCO: KEYNOTE-671 for neoadjuvant and adjuvant for the treatment of non- small cell lung cancer KEYTRUDA in combination with V9401, our Individualized Neoantigen Therapy (INT) for the treatment of adjuvant melanoma MK-28702, our TROP-2 ADC, for the treatment of non-small cell lung cancer Q Vaccines and Infectious Disease Announced positive topline results for V116, our pneumococcal conjugate vaccine candidate specifically designed for adults General Medicine Cardiometabolic Completed FDA submission of sotatercept in PAH based on the Phase 3 STELLAR trial Presented Phase 2a data at EASL for efinopegdutide, our GLP-1/ glucagon receptor co-agonist, in NAFLD Immunology Completed acquisition of Prometheus Biosciences 1. In collaboration with Moderna 2. In collaboration with Kelun MERCK 7#8Putting the patient at the center of everything we do Guided by our purpose to continue advancing innovative science and broadening access to patients around the world 1. Formerly called the ESG report 2022/2023 Impact Report¹ forthcoming MERCK 8#9MERCK INVENTING FOR LIFE Business/Financial Results and Outlook Caroline Litchfield Chief Financial Officer#10Strong underlying Q2 worldwide sales growth Merck WORLDWIDE SALES1,2 $15.0B +3% growth +11% ex-LAGEVRIO3 +14% ex-exchange, ex-LAGEVRIO3 Human Health $13.5B +6% growth +14% ex-LAGEVRIO3 +17% ex-exchange, ex-LAGEVRIO3 Animal Health $1.5B -1% growth +2% ex-exchange 1. Results attributable to Merck & Co., Inc. 2. Worldwide Sales includes Other Revenue. 3. Excludes Lagevrio sales of $203 million in 2Q23 and $1.2 billion in 2Q22. MERCK 10#11Oncology: KEYTRUDA continues to drive strong growth • KEYTRUDA sales of $6.3B increased 21% year-over-year, driven by uptake in earlier stage cancers and continued strong global demand from metastatic indications In the U.S., growth of 21% reflects strong utilization across earlier stage cancers such as TNBC, as well as certain types of RCC and melanoma KEYTRUDA (pembrolizumab) Injection 100 mg $6.3B +21% Ex-U.S., 22% increase driven by demand in metastatic RCC and certain types of H&N cancer, as well as earlier stage cancers, including high-risk early stage TNBC and RCC $5.3B +30% $4.2B +20% Growth rates exclude the impact of foreign exchange. 2Q21 2Q22 2Q23 MERCK 11#12Oncology: Solid performance across broad portfolio Lynparza • Lynparza¹ sales grew 15% driven primarily by increased demand in certain international markets Lenvima² sales grew 6% due to demand in advanced RCC and endometrial cancer in the U.S., partially offset by lower sales in China $248M +34% Growth rates exclude the impact of foreign exchange. 1. In collaboration with AstraZeneca 2. In collaboration with Eisai olaparib tablets 150 mg $310M $275M +15% +17% 2Q21 2Q22 2Q23 LENVIMA (lenvatinib) capsules 10mg and 4 g mg $181M +15% $231M +33% $242M +6% 2Q21 2Q22 2Q23 MERCK 12#13Vaccines: Exceptional growth driven by GARDASIL • • GARDASIL sales of $2.5B increased 53% year-over-year primarily driven by strong global demand, particularly in China - - China growth is benefitting from the expanded indication of GARDASIL 9 to females ages 9 to 45 Strong ongoing pediatric launch of VAXNEUVANCE GARDASIL. [Human Papillomavirus Quadrivalent (Types 6, 11, 16, and 18) Vaccine, Recombinant] $1.7B +40% GARDASIL.9 [Human Papillomavirus 9-valent Vaccine, Recombinant] $2.5B +53% Growth rates exclude the impact of foreign exchange. $1.2B +78% 2Q21 2Q22 2Q23 MERCK 13#14Hospital: Strong demand across key products bridion (sugammadex) 100 mg/mL Injection • BRIDION sales of $502M increased 19% primarily due to greater share among neuromuscular blockade reversal agents in the U.S. PREVYMIS sales grew 42% driven by continued strong global demand Growth rates exclude the impact of foreign exchange. $502M $426M $387M +67% +19% +15% 2Q21 2Q22 2Q23 $93M +41% PREVYMIS (letermovir) 240 mg, 480 mg tablets Injection 20 mg/mL $103M +18% $143M +42% 2Q21 2Q22 2Q23 MERCK 14#15Animal Health: Growth driven by livestock and companion animal • Animal Health sales increased 2% to $1.5B - Livestock growth of 2% reflects price actions and increased demand for swine and poultry products, partially offset by lower demand for ruminant products due in part to reduced herd sizes - Companion Animal growth of 2% reflects price actions including for BRAVECTO, partially offset by supply challenges for certain vaccines Growth rates exclude the impact of foreign exchange. MERCK Animal Health $1.5B +27% $1.5B +5% $1.5B +2% 2Q21 2Q22 2Q23 MERCK 15#16Q2 2023 non-GAAP financial results summary 1 $ in billions, except LPS/EPS amounts Change Q2 2023 Q2 2022 Change Ex-FX Sales $15.0 $14.6 +3% +7% Non-GAAP Gross Margin 76.6% 74.7% +1.9pts +2.7pts Non-GAAP Operating Expenses² $15.9 $5.2 N/M N/M Non-GAAP Tax Rate³ -18.4% 13.8% -32.2pts N/A Non-GAAP Earnings / (Loss) Per Share4 ($2.06) $1.87 N/M N/M 1. Merck is providing certain 2023 and 2022 non-GAAP information that excludes certain items because of the nature of these items and the impact they have on the analysis of underlying business performance and trends. Management believes that providing this information enhances investors' understanding of the company's results because management uses non-GAAP results to assess performance. Management uses non-GAAP measures internally for planning and forecasting purposes and to measure the performance of the company along with other metrics. In addition, senior management's annual compensation is derived in part using a non-GAAP pre-tax income metric. This information should be considered in addition to, but not as a substitute for or superior to, information prepared in accordance with GAAP. For a description of the non-GAAP adjustments, see Table 2a attached to the earnings release. 2. 2Q23 non-GAAP results include $10.2 billion of R&D expense or $4.02 of negative impact to EPS, related to the acquisition of Prometheus Biosciences. 3. Q2 2023 provision for Taxes on Income was $810 million. A pre-tax loss was recorded this quarter due to the Prometheus one-time charge, which was not tax deductible. As a result, the tax rate was negative in the quarter. 4. Q2 2023 GAAP LPS of ($2.35). MERCK 16#17Merck updated full-year 2023 guidance. Revenue Prior Guidance $57.7B to $58.9B -3% to -1% (-1% to +1% ex-FX) Updated Guidance $58.6B to $59.6B -1% to +1% (+1% to +3% ex-FX) Key Assumptions • Includes approximately $1B of LAGEVRIO revenue • Ex-LAGEVRIO, growth of 8% to 9% (10 to 11% ex-FX) Assumes 2 ppt FX headwind Non-GAAP Gross Margin Rate Non-GAAP ~77.0% ~77.0% • $23.3B to $24.1B $34.0B to $34.6B Operating Expenses¹ Other (Income) / Expense ~$250M of income ~$100M of expense Includes additional $10.2B related to upfront charge for the acquisition of Prometheus and investment to advance the acquired assets Includes financing costs related to the acquisition of Prometheus Tax Rate ~17.0% to 18.0% ~30.5% to 31.5% Includes ~15 ppt negative impact from the acquisition of Prometheus Shares Outstanding Non-GAAP EPS² ~2.55B $6.88 to $7.00 ~2.55B $2.95 to $3.05 • Assumes modest share repurchase Includes $4.02 one-time charge for the Prometheus acquisition and an additional $0.14 to advance the assets and finance the transaction Assumes 5 ppt FX headwind (additional $0.02 headwind) 1. Includes an aggregate $11.6 billion of R&D expenses related to the Prometheus and Imago acquisitions and upfront payment for the license and collaboration agreement with Kelun. Outlook does not assume any additional significant potential business development transactions. 2. Includes $4.53 of one-time charges related to the Prometheus and Imago acquisitions and upfront payment to Kelun. MERCK 17#18Key modeling considerations. • KEYTRUDA • • Anticipate strong year-over-year growth, but not quite at the levels experienced in recent quarters Continue to expect strong volume growth to be partially offset by pricing headwinds, particularly in key European markets In the second quarter, there was a small benefit from wholesaler purchase timing in the U.S. which is expected to reverse in the third quarter GARDASIL Expect the pace of full year growth to be higher in 2023 relative to 2022, with first half growth above that of the second half due in part to the timing of shipments in China MERCK 18#19Remain committed to balanced capital allocation strategy $ Billions¹ Capital allocation order of priority $10.9 $2.6 $1.9 $1.0 $0.3 After-Tax R&D CapEx Dividends Paid Business Development 2 (ex-divestitures) Share Repurchase 1. Reflects Q2 spend. 2. Includes payment for the Prometheus acquisition. Continue to invest in our pipeline and business while augmenting our pipeline with value enhancing business development MERCK 19#20MERCK INVENTING FOR LIFE Research Update Dr. Dean Li President, Merck Research Laboratories#21Driving value for patients and shareholders by progressing our pipeline Key regulatory milestones since the last earnings call: • In the U.S., the FDA: 。 Granted approval of Lynparza' in combination with abiraterone and prednisone in patients with deleterious or suspected deleterious BRCAM metastatic castration-resistant prostate cancer o Accepted sBLA for KEYTRUDA in combination with chemotherapy in patients with locally advanced unresectable or metastatic biliary tract cancer o Approved a new indication for PREVYMIS for prophylaxis of cytomegalovirus (CMV) disease in adult kidney transplant recipients at high risk ○ Accepted the re-submission of NDA for gefapixant in patients with refractory or unexplained chronic cough • In the EU, the EMA: o Accepted SMAA for KEYTRUDA in combination with trastuzumab and chemotherapy in patients with locally advanced unresectable or metastatic HER2-positive gastric or gastroesophageal junction adenocarcinoma o Received positive CHMP opinion for gefapixant in patients with refractory or unexplained chronic cough • In Japan, the PMDA: • 。 Granted approval of KEYTRUDA in patients with relapsed or refractory primary mediastinal B-cell lymphoma o Accepted sJNDA for KEYTRUDA in combination with chemotherapy in 1L treatment of locally advanced unresectable or metastatic gastric or gastroesophageal junction adenocarcinoma, as well as in patients with locally advanced unresectable or metastatic biliary tract cancer • Granted approval of VAXNEUVANCE in pediatrics In China, the CDE: 。 Granted approval of Koselugo¹ for the treatment of symptomatic, inoperable plexiform neurofibromas in pediatric patients with neurofibromatosis type I ages 3 years and older • • • • • Key data & clinical advancements since the last earnings call: Presented data across broad oncology portfolio at ASCO, including for KEYTRUDA (KN-671, KN-483, KN-581, KN-716, KN-826), Lenvima², Lynparza¹, WELIREG, mRNA-4157/V9403 (INT) and MK-2870/SKB2644 (TROP2 ADC) Announced positive topline results for KN-811 evaluating KEYTRUDA in combination with trastuzumab as 1L treatment in patients with HER2-positive advanced gastric or gastroesophageal junction adenocarcinoma in PD-L1 positive patients Announced Phase 3 KN-A18 trial met primary endpoint of progression-free survival in patients with newly diagnosed high-risk locally advanced cervical cancer Announced Phase 3 KN-756 trial met one of its dual primary endpoints of pathological complete response rate in patients with high-risk, early-stage ER+/HER2-breast cancer Presented Phase 2a data at EASL for efinopegdutide (MK-6024), an investigational GLP-1/glucagon receptor co-agonist, in patients with nonalcoholic fatty liver disease (NAFLD), which has advanced to Phase 2b in nonalcoholic steatohepatitis (NASH) Completed BLA submission of sotatercept for pulmonary arterial hypertension (PAH) to the FDA Announced positive topline results from two Phase 3 trials evaluating V116 in vaccine-naïve and previously vaccinated individuals 1. In collaboration with AstraZeneca 2. In collaboration with Eisai 3. In collaboration with Moderna 4. In collaboration with Kelun MERCK 21#22Continuing to advance our broader oncology program Clinical progress • • • KEYNOTE-756: Phase 3 trial met one of its dual primary endpoints of PCR for treatment of patients with high-risk early-stage ER+/HER2- breast cancer KEYNOTE-A18: Phase 3 trial met one of its primary endpoints of PFS for treatment of patients with high-risk locally advanced cervical cancer Promising data presented at ASCO: KEYNOTE-671: KEYTRUDA perioperative regimen reduced risk of disease recurrence, progression, or death by 42% in patients with resectable stage II, IIIA or IIIB NSCLC KEYNOTE-942: V9401 (INT) and KEYTRUDA reduced risk of distant metastasis or death by 65% in patients with stage III/IV melanoma following complete resection - Initiated Phase 3 trial for adjuvant treatment of high risk, stage II to IV melanoma MK-28702: Showed encouraging anti-tumor activity in patients with locally advanced or metastatic NSCLC Regulatory updates • PROpel: received FDA approval for Lynparza³ in combination with abiraterone and prednisone in patients with deleterious or suspected deleterious BRCA-mutated mCRPC KEYNOTE-966: sBLA for KEYTRUDA in combination with chemotherapy in patients with locally advanced unresectable or metastatic biliary tract cancer accepted for FDA review KEYNOTE-811: KEYTRUDA in combination with trastuzumab and chemotherapy showed significant improvement in PFS in 1L treatment of HER2- positive advanced gastric or GEJ adenocarcinoma in patients whose tumors were PD-L1 positive Received positive EMA opinion 1. In collaboration with Moderna 2. In collaboration with Kelun 3. In collaboration with AstraZeneca MERCK 22#23ID Progressing our broader pipeline Vaccines and Infectious Disease VACCINES V116, our investigational pneumococcal conjugate vaccine specifically designed for adults: - protects against serotypes that are responsible for ~85% of invasive pneumococcal disease in adults ages ≥651 - includes 8 serotypes that are currently not covered by approved vaccines, and are responsible for ~30% of invasive pneumococcal disease in adults ages ≥651 Announced positive topline data for V116 for two Phase 3 trials (STRIDE-3 and STRIDE-6) General Medicine CARDIOMETABOLIC • Completed FDA submission of sotatercept for the treatment of adults with PAH based on the Phase 3 STELLAR trial Presented positive data at EASL from the Phase 2a trial evaluating efinopegdutide, our investigational GLP-1/ glucagon receptor co-agonist, in patients with NAFLD and initiated Phase 2b trial in pre-cirrhotic NASH • Received FDA approval for PREVYMIS for prophylaxis of CMV disease for adult recipients of kidney transplant who are at high-risk of infection COUGH FDA accepted re-submission of the NDA for gefapixant in patients with refractory or unexplained chronic cough 1. Centers for Disease Control and Prevention, IPD serotype data 2019, as compiled from data provided through Active Bacterial Coresurveillance (ABCs). MERCK 23#24Accelerating our presence in immunology • • · MERCK Deep expertise in clinical trial design and execution Global clinical trial scale Proven track record of developing and implementing precision medicine strategies Emerging immunology discovery pipeline + Prometheus Biosciences • • . • Focused expertise in immunology Deep genetic and biological insights from Prometheus 360 Data Science Platform Risk-stratified biomarker approach Suite of immunology pipeline compounds MERCK 24#25MERCK INVENTING FOR LIFE Q&A Rob Davis Chairman & Chief Executive Officer Caroline Litchfield Chief Financial Officer Dr. Dean Li President, Merck Research Laboratories Peter Dannenbaum Vice President, Investor Relations#26Appendix MERCK 26#27Q2 2023 GAAP financial results summary $ in billions, except LPS/EPS amounts Q2 2023¹ Q2 2022 Change Change Ex-FX Sales $15.0 $14.6 +3% +7% Operating Expenses $16.0 $5.3 N/M N/M Tax Rate -11.9% 12.0% -23.9pts N/A GAAP Earnings / ($2.35) $1.55 N/M N/M (Loss) per Share 1.2Q23 GAAP results include $10.2 billion or $4.02 of such charges related to the acquisition of Prometheus Biosciences. MERCK 27#28Capital allocation: Trailing twelve months. Over the past 12 months $15 $12 $9 $10.4 $6 Billions is is in in $3 $0 Order of priority $13.8 $7.2 $4.2 After-Tax R&D CapEx Dividends Paid Business $0.5 Share Development1 Repurchase (ex-divestitures) Capital investments 2023 to 2027 ~$15B Over 5 years, including expanding manufacturing capacity for Oncology, Vaccines, and Animal Health. Includes >$10B in the U.S. 1. Includes payments reflected in operating cash flow Dollars per share Well positioned balance sheet with capacity to fund additional value-enhancing business development opportunities Commitment to the dividend $3.20 +6% $2.90 +6% +7% $2.92 $2.60 +11% $2.76 +15% $2.60 $2.30 $2.44 $2.00 +2% +2% +2% +2% +2% $2.20 $1.70 $1.76 $1.80 $1.84 $1.88 $1.92 $1.40 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023E MERCK 28#29Broad and innovative pipeline to solve significant unmet medical needs Phase 2 Oncology MK-0482 NSCLC MK-2870 Neoplasm Malignant MK-4830 CRC WELIREG (MK-6482) Biliary MK-7684A (vibostolimab MK-1308 (quavonlimab) KEYTRUDA (MK-3475) Melanoma Esophageal Certain VHL tumors (EU) +pembrolizumab) CRC Biliary NSCLC Advanced Solid Tumors NSCLC Endometrial Bladder Prostate Ovarian Esophageal Breast MK-1308A RCC HCC Cervical MK-3543 (quavonlimab SCLC Pancreatic CRC (bomedemstat) +pembrolizumab) Rare Cancers Endometrial Myeloproliferative CRC MK-5684 Esophageal Disorders HCC Prostate TUKYSA (MK-7119) Gastric Melanoma MK-4280 Advanced Solid Tumors HCC SCLC (favezelimab) MK-5890 (boserolimab) Bladder HNSCC NSCLC NSCLC Biliary MK-2140 (zilovertamab SCLC Cervical Hematological Malignancies Ovarian vedotin) MK-4280A Endometrial Bladder (favezelimab+pembroli LYNPARZA (MK-7339) Prostate Gastric Breast zumab) Advanced Solid Tumors NSCLC Gastric Bladder LENVIMA (MK-7902) SCLC Hematological Malignancies Esophageal Biliary NSCLC Ovarian Pancreas Melanoma RCC SCLC Pancreas Prostate Oncology Phase 3 KEYTRUDA (MK-3475) CSCC (EU) Hepatocellular (EU) Mesothelioma Ovarian SCLC MK-1026 (nemtabrutinib) Hematological Malignancies MK-1308A (quavonlimab +pembrolizumab) RCC MK-7684A (vibostolimab +pembrolizumab) Melanoma LENVIMA (MK-7902) Esophageal Gastric HNSCC NSCLC LYNPARZA (MK-7339) NSCLC SCLC WELIREG (MK-6482) RCC Oncology Under regulatory review KEYTRUDA (MK-3475) 2L HCC (US) LA Merkel Cell (US) Adjuvant NSCLC (EU) HER2+ Gastric (EU) Resectable NSCLC (US, EU) 1L HER2- Gastric (US, EU, JPN) 1L Biliary (US, EU, JPN) LYNPARZA (MK-7339) Metastatic 1L Prostate (JPN) General medicine TUKYSA (MK-7119) Breast CRC Gefapixant (MK-7264) Cough (US, EU) MK-3475A NSCLC (pembrolizumab SCLC +hyaluronidase) NSCLC MK-4280A (favezelimab +pembrolizumab) V940 CRC Melanoma Hematological Malignancies Vaccines V181 Dengue Virus Infectious diseases MK-8591B (islatravir+MK-8507)¹ HIV-1 Infection MK-8591D (islatravir+lenacapavir)² HIV-1 Infection Cardiovascular MK-0616 Hypercholesterolemia MK-2060 Thrombosis MK-5475 Pulmonary Arterial Hypertension MK-7962 (sotatercept) Pulmonary Hypertension due to Left Heart Disease 1 On FDA clinical hold 2On FDA partial clinical hold for higher doses than those used in current clinical trials 3Available in the US under EUA 4Development is co-funded by Royalty Pharma 5Requested re-examination of EU MAA following CHMP major objection of data to support market authorization General medicine MK-1942 Treatment Resistant Depression MK-6024 (efinopegdutide) NASH Neuroscience MK-81894 Schizophrenia Immunology MK-7240 Ulcerative Colitis Infectious diseases MK-8591A (doravirine+islatravir)² HIV-1 Infection LAGEVRIO (MK-4482)³ COVID-19 antiviral Vaccines MK-1654 (clesrovimab) V116 Respiratory Syncytial Virus (RSV) adult Pneumococcal vaccine, Cardiovascular MK-7962 (sotatercept) Pulmonary Arterial Hypertension 29 As of August 2, 2023